Results 41 to 50 of about 1,068 (138)
The Journal of Dermatology, EarlyView.ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe +4 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
Letter in Reply: Important Points in Toxic Epidermal Necrolysis Management
Oman Medical Journal, 2019 Classically, toxic epidermal necrolysis (TEN) is considered as part of a group of cutaneous hypersensitivity reaction with a spectrum of severity, erythema multiforme (EM) followed by Stevens-Johnson syndrome (SJS), and TEN.
Lutfi Al-Kathiri
doaj +1 more source
Epidermal necrolysis: SCORTEN performance in AIDS and non-AIDS patients [PDF]
Anais Brasileiros de Dermatologia, 2019 : Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening blistering drug reactions with high incidence of ocular sequela.
Carlos Gustavo Wambier +8 more
doaj +1 more source
Journal of Education, Health and Sport, 2022 Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, acute conditions, potentially life-threatening, immune-mediated and often unpredictable.
Martyna Rozenbajgier +3 more
doaj +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
Allergy, EarlyView.ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
Important Points in Toxic Epidermal Necrolysis Management
Oman Medical Journal, 2019 There are several important points that the authors did not highlight which are critical and form the cornerstones in the care of patients with possible TEN.
Sultan
doaj +1 more source
INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol
BJU International, EarlyView.Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan +13 more
wiley +1 more source
Toxic epidermal necrolysis in a 5-year-old boy - case report
Brazilian Dental Science, 2016 Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are considered a spectrum of acute life-threatening mucocutaneous reaction that differ only in severity, often induced by drugs.
Pavan Puri +5 more
doaj +1 more source
Cutaneous approach in toxic epidermal necrolysis [PDF]
Revista Brasileira de Cirurgia Plástica, 2017 INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality.
Francisco Carlos Santos Neto +6 more
doaj +1 more source