Results 61 to 70 of about 17,156 (210)

Relationship between the HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson Syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis [PDF]

, 2013
IMPORTANCE: The US Food and Drug Administration recommends screening for the HLA-B*1502 allele before initiation of carbamazepine therapy in patients of Asian ancestry, but there remains unclear evidence of a relationship between HLA-B*1502 and Stevens ...
Chaiyakunapruk, Nathorn, Lohitnavy, Manupat, Somkrua, Ratchadaporn, Tangamornsuksan, Wimonchat, Tassaneeyakul, Wichittra   +4 more
core   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Toxic Epidermal Necrolysis Associated with Misoprostol: A Case Report

International Medical Case Reports Journal, 2023
Okbu Frezgi,1 Mulugeta Russom2– 4 1Gynecology and Obstetric Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea; 2Eritrean Pharmacovigilance Centre, National Medicines and Food Administration, Ministry of Health, Asmara, Eritrea ...
Frezgi O, Russom M
doaj  

Nécrolyse épidermique : Mécanisme de l’apoptose des kératinocytes [PDF]

, 2006
Les syndromes de Stevens-Johnson et de Lyell sont regroupés sous le nom de nécrolyse épidermique. Il s’agit de maladies bulleuses mucocutanées aiguës, rares mais extrêmement graves, provoquées le plus souvent par une « allergie » médicamenteuse.
Bensussan, Armand, Gélard, Kristel, Roujeau, Jean-Claude   +2 more
core   +1 more source

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda, B. Tedbirt, C. Bodemer, M. C. Bolling, M. El Hachem, M. Nikolić, E. Benton, M. Caproni, D. De, D. Didona, K. Drenovska, M. Goebeler, M. Hertl, B. Horváth, M. Kasperkiewicz, D. Kiritsi, M. Larralde, A. V. Marzano, J. Meijer, D. F. Murrell, J. Powell, E. Sprecher, N. S. Chandran, M. M. Tomayko, S. Uzun, N. van Beek, H. Ott, A. Patsatsi, A. Torrelo, A. Welfringer‐Morin, E. Schmidt, P. Joly   +31 more
wiley   +1 more source

Deep cutaneous Trichosporon asahii infection in a patient recovering from toxic epidermal necrolysis

Medical Mycology Case Reports, 2019
Patients with toxic epidermal necrolysis, a condition that causes full thickness epidermal necrosis that affects over 30% of the skin surface and mucosal membranes, often develop comorbid infections throughout the recovery of the disease [1].
John L. Kiley, Jason Zack, Simon Ritchie, Kevin Krauland, Elizabeth Markelz   +4 more
doaj   +1 more source

Toxic Epidermal Necrolysis After Topical Intranasal Application of Mupirocin [PDF]

, 2017
We describe a case of toxic epidermal necrolysis after intranasal application of mupirocin in a 76-year-old woman.
de Torrenté, Antoine, Genné, Daniel, Praz, Sophie-Maria, Schleppy, Charles-André, Schmied, Edmond, Zender, Hervé   +5 more
core  

Ocular Manifestations of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis [PDF]

, 2016
Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare and sometimes life-threatening hypersensitivity mucocutaneous disease triggered mostly by medication and infections Major involving tissues are the mucous membranes of oral ...
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core   +1 more source

Diagnosis and Management of Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Systematic Review of Clinical Guidelines and Consensus Statements

Pediatric Dermatology, EarlyView.
ABSTRACT Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life‐threatening mucocutaneous reactions. Pediatric mortality is lower than in adults, but children face higher risks of recurrence and long‐term sequelae. Despite disease severity, pediatric‐specific guidelines remain scarce and often extrapolated from adult ...
Rachel Creighton, Sana Gupta, Courtney Langille, Ashley Sutherland   +3 more
wiley   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

Contact Dermatitis, Volume 94, Issue 6, Page 677-688, June 2026.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam   +8 more
wiley   +1 more source