Results 21 to 30 of about 29,800 (242)
Toxic Epidermal Necrolysis Post COVID-19 Vaccination - First Reported Case
Cureus, 2021 Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a spectrum of acute, delayed-type hypersensitivity reactions that affect the skin and the mucous membranes.
M. Bakir +4 more
semanticscholar +1 more source
Science Advances, 2021 This study highlights the key role of polycytotoxic CD8+ T cells in the severity of toxic epidermal necrolysis. Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous adverse drug reaction.
A. Villani +24 more
semanticscholar +1 more source
Fulvestrant-induced toxic epidermal necrolysis [PDF]
Anais Brasileiros de Dermatologia, 2019 Toxic epidermal necrolysis is a condition with massive keratinocyte apoptosis, and it is associated with high mortality rates. Fulvestrant, an estrogen receptor antagonist, is indicated in the treatment of estrogen receptor-positive metastatic breast ...
Macarena Morales-Conde +3 more
doaj +1 more source
Pembrolizumab-Induced Toxic Epidermal Necrolysis
Case Reports in Oncology, 2022 Immunotherapy has nowadays become part of the mainstay of treatment for several cancers. In this report, we present a case of toxic epidermal necrolysis (TEN) occurring as a relatively rare complication of pembrolizumab, which is a humanized monoclonal ...
Luca Borg +5 more
doaj +1 more source
F1000Research, 2020 Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening diseases characterized by detachment of the epidermis and mucous membrane.
A. Hasegawa, R. Abe
semanticscholar +1 more source
Current Pharmacogenetic Perspective on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Frontiers in Pharmacology, 2021 Adverse drug reactions are a public health issue that draws widespread attention, especially for Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) which have high mortality and lack of efficacious treatment.
Lin Cheng
semanticscholar +1 more source
Identifying the incidence of rash, Stevens-Johnson syndrome and toxic epidermal necrolysis in patients taking lamotrigine: a systematic review of 122 randomized controlled trials [PDF]
Anais Brasileiros de Dermatologia, 2017 Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic
Romi Bloom, Kyle T. Amber
doaj +2 more sources
Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Associated With Mebendazole Use [PDF]
Basic Clin Pharmacol ToxicolBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
Heerfordt I +4 more
europepmc +2 more sources
Toxic Epidermal Necrolysis and Steven-Johnson Syndrome: A Comprehensive Review.
Advances in wound care, 2020 Significance: Toxic epidermal necrolysis (TEN) and Steven-Johnson syndrome (SJS) are potentially fatal acute mucocutaneous vesiculobullous disorders.
Olivia A. Charlton +5 more
semanticscholar +1 more source
The Journal of Emergency Medicine, 1989 Toxic epidermal necrolysis (TEN) is a life-threatening condition in which the epidermis blisters and peels in large sheets. The clinical syndrome and diagnosis are reviewed. Current treatment and prevention of complications are discussed. The key to low morbidity and mortality in TEN is early intervention.
Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA ( host institution ) +4 more
openaire +7 more sources