Results 61 to 70 of about 29,800 (242)

Toxic Epidermal Necrolysis Associated with Misoprostol: A Case Report

open access: yesInternational Medical Case Reports Journal, 2023
Okbu Frezgi,1 Mulugeta Russom2– 4 1Gynecology and Obstetric Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea; 2Eritrean Pharmacovigilance Centre, National Medicines and Food Administration, Ministry of Health, Asmara, Eritrea ...
Frezgi O, Russom M
doaj  

Cephazolin-Induced Toxic Epidermal Necrolysis Treated with Intravenous Immunoglobulin and N-Acetylcysteine

open access: yesCase Reports in Immunology, 2012
Toxic epidermal necrolysis is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and ...
Carlos Saavedra   +4 more
doaj   +1 more source

Toxic epidermal necrolysis associated with severe cytomegalovirus infection in a patient on regular hemodialysis.

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2011
Primary illness with cytomegalovirus leads to latent infection with possible reactivations especially in the immunocompromised patients. Toxic epidermal necrolysis is an immune mediated cytotoxic reaction.
Dina Khalaf   +3 more
doaj   +1 more source

Diagnosis and Management of Hypersensitivity to Antiplatelet Drugs: EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT Antiplatelet drug (APD) therapy is the cornerstone for the prevention of atherosclerotic cardiovascular disease. The main APDs are aspirin and thienopyridines, particularly clopidogrel. These drugs may induce hypersensitivity reactions (HSRs).
Gabriele Cortellini   +10 more
wiley   +1 more source

Lamotrigine and anti‐seizure medications in HLH: A systematic review

open access: yesBritish Journal of Haematology, EarlyView.
Lamotrigine and other anti‐seizure medications have been reported to cause both haemophagocytic lympho‐histiocytosis (HLH) and drug‐induced hypersensitivity syndrome (DIHS). HLH and DIHS have many characteristic clinical, laboratory, pathological findings and underlying mechanisms; we identified significant clinical overlap between these two syndromes ...
Yaswanta K. Gummadi   +4 more
wiley   +1 more source

The application of comet assay in monitoring of the immunosuppression level in a patient with toxic epidermal necrolysis: A case report

open access: yesBurns Open, 2017
Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový   +8 more
doaj  

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Toxic epidermal necrolysis

open access: yesPhilippine Journal of Ophthalmology, 2011
Objective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care.
Rosalie Mae M. Reyes, MD   +1 more
doaj  

Epidermal necrolysis (Stevens–Johnson syndrome and toxic epidermal necrolysis): Historical considerations

open access: yesDermatologica Sinica, 2013
Objective: To describe the history of toxic epidermal necrolysis, before and after the original report by the British dermatologist Alan Lyell in 1956. Methods: Subjective expert choice of key advances in the comprehension of the nosology, classification,
Jean-Claude Roujeau
doaj   +1 more source

Toxic Epidermal Necrolysis A Diagnostic Dilemma in Puerperium: A Case Report

open access: yesJournal of Nepal Medical Association, 2019
Toxic epidermal necrolysis is a potentially life threatening dermatologic disorder characterized by widespread erythema, necrosis and bullas, detachment of epidermis and mucous membrane resulting in exfoliation, possible sepsis and even death.
Vidya Mahto   +2 more
doaj   +1 more source

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