Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Some plants may only be known by the people in their own respective place. Consequently, there is a need for the authentication and further study of wild toxic plant known by indigenous people.
Dana Theresa C. De Leon +3 more
doaj +1 more source
Heavy metal concentrations exceeding permissible limits threaten human life, plant life, and all other life forms. Different natural and anthropogenic activities emit toxic heavy metals in the soil, air, and water.
Ujala Ejaz +9 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The influence of technological processing on the concentration levels of natural and synthetic toxic substances present in agricultural plants and their products and determination methods of toxins [PDF]
Magdalena Jankowska, Bożena Łozowicka
openalex +1 more source
Cadmium and arsenic affect root development in Oryza sativa L. negatively interacting with auxin [PDF]
Cadmium (Cd) and arsenic (As), non essential, but toxic, elements for animals and plants are frequently present in paddy fields. Oryza sativa L., a staple food for at least the half of world population, easily absorbs As and Cd by the root, and in this ...
Altamura, M. M. +7 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Phytochemical screening and acute toxicity assessment of leaves from Piliostigma thonningii (Fabaceae), a plant used in traditional medicine against diabetes in Côte d’Ivoire [PDF]
Doh Koffi Stéphane +3 more
openalex +1 more source
Technological learning for innovating towards sustainable cultivation practices: the Vietnamese smallholder rose sector [PDF]
Deregulation and globalisation has altered the views of public involvement in development and led to strategies focusing on private sector participation.
Danse, M.G. +3 more
core +3 more sources

