Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
O uso de extratos de plantas, em grande parte ainda inexplorada na Amazônia, constitui uma alternativa para o controle de insetos fitófagos, devido o baixo custo operacional, facilidade de preparação, utilização e segurança para o meio ambiente.
Wilson Castro Silva+3 more
doaj +1 more source
Comparative transcriptomes reveal geographic differences in the ability of the liver of plateau zokors (Eospalax baileyi) to respond and adapt to toxic plants. [PDF]
Tan Y+5 more
europepmc +1 more source
Justice in the Air: Tracking Toxic Pollution from America's Industries and Companies to Our States, Cities, and Neighborhoods [PDF]
This new environmental justice study, (co-authored by PERI’s James Boyce, Michael Ash, & Grace Chang, along with Manuel Pastor, Justin Scoggins, & Jennifer Tran of the Program for Environmental and Regional Equity at the University of Southern California)
Grace Chang+4 more
core
Biological Agents of Bioremediation: A Concise Review [PDF]
Due to intensive agriculture, rapid industrialization and anthropogenic activities have caused environmental pollution, land degradation and increased pressure on the natural resources and contributing to their adulteration.
Biswas, Karabi
core
Toxic Phenolic Glycosides From \u3ci\u3ePopulus:\u3c/i\u3e Physiological Adaptations of the Western North American Tiger Swallowtail Butterfly, \u3ci\u3ePapilio Rutulus\u3c/i\u3e (Lepidoptera: Papilionidae) [PDF]
The phenolic glycosides tremulacin and salicortin found in quaking aspen, Populus tremuloides, and other members of the Salicaceae, are known to be toxic to larvae of the Eastern tiger swallowtail butterfly, Papilio glaucus, but not to the Canadian tiger
Lindroth, Richard L+2 more
core +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Intoxicação por Amorimia spp. em ruminantes Poisoning by Amorimia spp. in ruminants
No Brasil, um dos grupos mais importantes de plantas tóxicas é o das que causam morte súbita associada ao exercício. Integram esse grupo, plantas das famílias Rubiaceae, Bignoniaceae e Malpighiaceae.
Amélia Lizziane Duarte+2 more
doaj
Plantas tóxicas para suínos Toxic plants for swine
Revisam-se as intoxicações por plantas que ocorrem em suínos no Brasil, Uruguai e Argentina. Descrevem-se a intoxicação por sementes de Senna occidentalis, que causa necrose muscular segmentar e lesões hepáticas, e a intoxicação por sementes de ...
Cláudio Dias Timm+1 more
doaj +1 more source
Aquatic plants for removal of mevinphos from the aquatic environment [PDF]
Fragrant waterlily (Nymphaea odorata, Ait.), joint-grass (Paspalum distichum L.), and rush (Juncus repens, Michx.) were used to evaluate the effectiveness of vascular aquatic plants in removing the insecticide mevinphos (dimethyl-1-carbomethoxy-1propen-2-
Wolverton, B. C.
core +1 more source