Results 121 to 130 of about 173,637 (297)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Inventory of Toxic Plants in Morocco: An Overview of the Botanical, Biogeography, and Phytochemistry Studies. [PDF]

J Toxicol, 2018
Benzeid H, Gouaz F, Touré AH, Bouatia M, Idrissi MOB, Draoui M.   +5 more
europepmc   +1 more source

Function of ZnO Nanoparticles in the Remediation of the Toxic Metal, Seed Germination, and Seedling Growth of the Plant, Synthesized by Stem Extracts of Anthophalus cadamba

, 2022
Shaik Abdul Mathin, M David Raju, Devi Narla Rama, Sekhara Reddy, V Soni, P Raizada, P Singh, H Cuong, S, R Saini, A Saini, R Le, Q Nadda, A Le, T.-T Nguyen, V.-H, F Behzad, S Naghib, M Tabatabaei, S Zare, Y Rhee, K, L Castillo-Henrquez, K Alfaro-Aguilar, J Ugalde-lvarez, L Vega-Fernndez, G Montes De Oca-Vsquez, J Vega-Baudrit, S Alnadhari, N Al-Enazi, F Alshehrei, F Ameen, R Jurkow, R Pokluda, A Skara, A Kalisz, H Sayed Ahmed, D Elsherif, A El-Shanshory, A Haider, R Gaafar, S Batool, B Javed, S Sohail; Zehra, Z.-U.-R Mashwani, N Raja, T Khan, H Alhaithloul, S Alghanem, A Al-Mushhin, M Hashem, S Alamri, E Skiba, M Pietrzak, S Gliska, W Wolf, P Rani, G Kaur, K Rao, J Singh, M Rawat, Y Singh, S Kaushal, R Sodhi, P Itroutwar, G Kasivelu, V Raguraman, K Malaichamy, S Sevathapandian, H Baz, M Creech, J Chen, H Gong, K Bradford, H Huo, I Toqeer, A Naz, M Ghaffar, A Hussain, Z Ghuffar, A, W Wang, Y Ren, J He, L Zhang, X Wang, Z Cui, K Zhang, Y Wang, J Mao, B Chen, A Dwevedi, K Sharma, Y Sharma, Cadamba, T Zhang, H Sun, Z Lv, L Cui, H Mao   +99 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Anticholinergic syndrome induced by toxic plants. [PDF]

World J Emerg Med, 2017
Soulaidopoulos S, Sinakos E, Dimopoulou D, Vettas C, Cholongitas E, Garyfallos A.   +5 more
europepmc   +1 more source

MEASUREMENT OF TOXIC METAL CONTAMINATION, PHENOLIC AND FLAVONOID CONTENTS, ANTICANCER, ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF DIETARY AND MEDICINAL PLANT JUGLANS REGIA L.

, 2018
Nosheen Azhar
openalex   +1 more source

Signal peptide‐regulated toxicity of a plant ribosome‐inactivating protein during cell stress [PDF]

, 2010
Richard S. Marshall, Francesca D’Avila, Alessandra Di Cola, Roberta Traini, Laura Spanò, Maria Serena Fabbrini, Aldo Ceriotti   +6 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source