Plant toxins: alkaloids and their toxicities [PDF]
GSC Biological and Pharmaceutical Sciences, 2018 Since ancient civilization, plants have been utilized in many aspects of life, especially in medicinal purposes due to the presence of distinctive secondary metabolites like alkaloids, phenolics and terpenoids. Among them, alkaloids represent a large group of secondary metabolites that have basic properties and comprise nitrogen atom within the ...
Mohamad Azzeme, Azzreena +1 more
openaire +2 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Nitrate and nitrite poisoning in sheep and goats caused by ingestion of Portulaca oleracea
Pesquisa Veterinária Brasileira: Three outbreaks of poisoning by Portulaca oleracea were reported in sheep and goats in Northeast Brazil. In the first outbreak, 8 out of 20 sheep were affected and later died.
João G. Simões +5 more
doaj +1 more source
Evaluation of the genotoxic and teratogenic potential of a municipal sludge and sludge-amended soil using the amphibian Xenopus laevis and the tobacco: Nicotiana tabacum L. var. xanthi Dulieu [PDF]
, 2003 The toxic, genotoxic and teratogenicpotential of amunicipal sewage sludge was assessed using the micronucleus assay on the larvae of the amphibianXenopuslaevis and with the tobacco somatic mutation test using the yellow–green xanthiDulieu mutant a1+/a1 ...
Chenon, Pascale +4 more
core +2 more sources
Nitrite Toxicity to Plants [PDF]
Nature, 1966 IT is generally believed that nitrite is an intermediate product in the conversion of ammonium to nitrate in the soil where the conversion of nitrite to nitrate is important since relatively small quantities may have toxic effects on plant growth. Nitrite is not a stable intermediate and few cases of nitrite accumulation in soils are reported.
openaire +2 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Spontaneous and experimental poisoning by Myrocarpus frondosus in cattle
Pesquisa Veterinária Brasileira: An outbreak of photosensitization in Holstein and Jersey cattle occurred after the passage of an extratropical cyclone in Southern Brazil. On that occasion, several trees fell, including some of the species Myrocarpus frondosus (Fabaceae family ...
Tainara R. Tineli +5 more
doaj +1 more source
PERSPECTIVES OF STUDYING OF SPECIES OF FAMILY CRASSULACEAE DC. IN KRYVYI RIH AREA WITH REFERENCE TO PHYTOREMEDIATION AND PHYTOMINING [PDF]
, 2018 To search plants-hyperaccumulators is one of the most promising directions of biological methods for removing of toxic compounds from ecosystems. Screening acquires special importance for species, which will be used to create phytocoenoses in large ...
Krasova, Olha
core
Exploring the anthelmintic properties of Australian native shrubs with respect to their potential role in livestock grazing systems [PDF]
, 2009 We measured in vitro anthelmintic activity in extracts from 85 species of Australian native shrub, with a view to identifying species able to provide a degree of worm control in grazing systems.
A. C. KOTZE +17 more
core +2 more sources
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source