Results 51 to 60 of about 173,637 (297)
Techniques for prevention and control of poisoning by sodium monofluoroacetate (MFA)-containing plants in ruminants [PDF]
Pesquisa Veterinária Brasileira, 2019 : Monofluoroacetate (MFA)-containing plants cause sudden death associated with exercise in ruminants, and are responsible for significant losses in Brazilian livestock, estimated at 500,000 bovine deaths annually.
Danielle A.N. Pessoa +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Datura poisoning in a family: Case series and literature review
Clinical Case Reports, 2022 Datura spp. is a potentially poisonous plant that is widely spread and is simply accessible, which can yield poisoning with a central and peripheral anticholinergic effect.
Niloofar Khoshnam‐Rad +5 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Toxic ornamental plants in Venezuela
Bonplandia, 2017 The aim of this research was to contribute information on toxic ornamental plants in Venezuela. Information on taxonomy, common names, habit, origin, status, location, propagation and toxicology (part of the plant, effects) was compiled from articles ...
Carlos Varela Romero +2 more
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Holiday Plants with Toxic Misconceptions
Western Journal of Emergency Medicine, 2012 Several plants are used for their decorative effect during winter holidays. This review explores the toxic reputation and proposed management for exposures to several of those, namely poinsettia (Euphorbia pulcherrima), English holly (Ilex aquifolium ...
Zabrina N. Evens, Samuel J. Stellpflug
doaj
HPLC-DAD-MS/MS chemical characterization and evaluation of poisoning by Vernonia rubricaulis in sheep and mice [PDF]
Pesquisa Veterinária Brasileira: Vernonia rubricaulis is a plant responsible for poisoning cattle living in areas subject to flooding in the Pantanal biome of Brazil. Because V. rubricaulis causes acute hepatic necrosis and clinical signs and lesions similar to other hepatotoxic ...
Carolina C. Guizelini +6 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source