Results 81 to 90 of about 526,068 (354)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Toxic ornamental plants in Venezuela

open access: yesBonplandia, 2017
The aim of this research was to contribute information on toxic ornamental plants in Venezuela. Information on taxonomy, common names, habit, origin, status, location, propagation and toxicology (part of the plant, effects) was compiled from articles ...
Carlos Varela Romero   +2 more
doaj  

Endocidal Regulation of Secondary Metabolites in the Producing Organisms [PDF]

open access: yes, 2016
Secondary metabolites are defined as organic compounds that are not directly involved in the normal growth, development, and reproduction of an organism.
Bullard, Steven H   +4 more
core   +2 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Aversion and attraction to harmful plant secondary compounds jointly shape the foraging ecology of a specialist herbivore. [PDF]

open access: yes, 2016
Most herbivorous insect species are restricted to a narrow taxonomic range of host plant species. Herbivore species that feed on mustard plants and their relatives in the Brassicales have evolved highly efficient detoxification mechanisms that actually ...
Alexandre, Nicolas   +8 more
core  

Food plant toxicants and safety [PDF]

open access: yesEnvironmental Toxicology and Pharmacology, 1998
The ADI as a tool for risk management and regulation of food additives and pesticide residues is not readily applicable to inherent food plant toxicants: The margin between actual intake and potentially toxic levels is often small; application of the default uncertainty factors used to derive ADI values, particularly when extrapolating from animal data,
Jan H. Koeman   +15 more
openaire   +5 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Cardiac Glycoside Plants Self-Poisoning

open access: yesActa Medica Bulgarica, 2014
Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander, Convallaria majalis (lily of the valley), Strophanthus gratus, etc.
Radenkova-Saeva J., Atanasov P.
doaj   +1 more source

Experimental poisoning by Crotalaria lanceolata and Crotalaria pallida seeds in broilers [PDF]

open access: yesPesquisa Veterinária Brasileira, 2019
: Crotalaria lanceolata E. Mey. and Crotalaria pallida Aiton. are leguminous plants of family Fabaceae found in most of the Brazilian territory. They were initially used as green manure and due their easy spread they are currently considered weeds in ...
Thaiza Savaris   +7 more
doaj   +1 more source

The use of simulated whole effluents in toxicity assessments: A review of case studies from reverse osmosis desalination plants [PDF]

open access: yes, 2014
Seawater desalination is an increasingly common means to meet the demand for freshwater. Resulting wastewater discharges can, however, impact biota of the surrounding environment.
Falkenberg, LJ, Styan, CA
core  

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