Results 91 to 100 of about 2,508,230 (293)
Scientific ReportsRecently, there have been reports of sarcoma occurring in a Korean science teachers who used a 3D printer with acrylonitrile butadiene styrene (ABS) and polylactic acid (PLA) filaments for educational purposes.
CheolHong Lim, DongSeok Seo
doaj +1 more source
Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver. [PDF]
, 2007 We administered an adenoviral vector, Onyx-015, into the hepatic artery of patients with metastatic colorectal cancer involving the liver. Thirty-five patients enrolled in this multi-institutional phase I/II trial received up to eight arterial infusions ...
Au, T +5 more
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Recreational use, analysis and toxicity of tryptamines [PDF]
, 2015 The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Bioavailability of pesticides in freshwater sediments [PDF]
, 2007 In ecological risk assessment standardized sediment toxicity tests are used to predict the hazard of chemicals for sediment-living organisms. Feeding is a prerequisite in these long-term tests to avoid starvation of test organisms.
Åkerblom, Nina
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TOXICITY OF PREDNISOLONE, DEXAMETHASONE AND THEIR PHOTOCHEMICAL DERIVATIVES ON AQUATIC ORGANISMS [PDF]
, 2004 Light exposure of aqueous suspensions of prednisolone and dexamethasone causes their partial phototransformation. The photoproducts, isolated by chromatographic techniques, have been identified by spectroscopic means.
DELLA GRECA, MARINA +6 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A brief introduction to the United States CDC Laboratory Response Network for Chemical Threats
Zhongguo gonggong weishengThe United States Centers for Disease Control and Prevention (CDC) Laboratory Response Network for Chemical Threats (LRN-C) is a network of more than 50 primarily local public health laboratories covering all states and regions of the United States.
Xuefei LENG, Yimin WEN
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PPAR Research, 2010 Peroxisome proliferator-activated receptors (PPARs) regulate lipid and glucose homeostasis, are targets of pharmaceuticals, and are also activated by environmental contaminants.
Barbara D. Abbott +4 more
doaj +1 more source
The effects of two pesticides on Clarias gariepinus [PDF]
, 1993 Bioassays were carried out to determine the toxicity of two pesticides, Roundup and Gramoxone on Clarias gariepinus. The acute toxicity of both pesticides decreased towards the end of the bioassay period.
Mulero, O. +2 more
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