Results 91 to 100 of about 2,730,331 (342)

Oxidative damage in metal fragment-embedded Sprague-Dawley rat gastrocnemius muscle

Current Research in Toxicology, 2022
Injuries suffered in armed conflicts often result in wounds with embedded metal fragments. Standard surgical guidance has been to leave fragments in place except under certain circumstances; meaning that individuals may carry these retained fragments for
John F. Kalinich, Vernieda B. Vergara, Jessica F. Hoffman   +2 more
doaj  

Challenges for the development of a biotic ligand model predicting copper toxicity in estuaries and seas [PDF]

, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 SETAC.An effort is ongoing to develop a biotic ligand model (BLM) that predicts copper (Cu) toxicity in estuarine and marine ...
de Polo, A, Scrimshaw, MD
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Homeopathic dosing and combined dosing of β-nicotinamide mononucleotide and taurine on experimental silicosis in rats

环境与职业医学
BackgroundPneumoconiosis is a chronic inflammatory disease that cannot be completely cured. Therefore, how to control lung inflammation and delay of the body aging is one of the keys to treating pneumoconiosis.
Yongjin GAN, Ruize CHEN, Jian’an LING, Yanni HUANG, Danyu LIANG   +4 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Peroxisome Proliferator-Activated Receptors Alpha, Beta, and Gamma mRNA and Protein Expression in Human Fetal Tissues

PPAR Research, 2010
Peroxisome proliferator-activated receptors (PPARs) regulate lipid and glucose homeostasis, are targets of pharmaceuticals, and are also activated by environmental contaminants.
Barbara D. Abbott, Carmen R. Wood, Andrew M. Watkins, Kaberi P. Das, Christopher S. Lau   +4 more
doaj   +1 more source

Prevalence, risk factors and seasonal variations of different Enteropathogens in Lebanese hospitalized children with acute gastroenteritis

BMC Pediatrics, 2019
Background Acute gastroenteritis (AGE) is a major cause of pediatric morbidity and mortality around the world. It remains a frequent reason for infection-related admissions to emergency units among all age groups.
Ali Salami, Hadi Fakih, Mohamed Chakkour, Lamis Salloum, Hisham F. Bahmad, Ghassan Ghssein   +5 more
doaj   +1 more source

Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary cells in the presence of adenovirus [PDF]

, 1994
Endotoxin (lipopolysaccharide, LPS) is commonly found as a contaminant in plasmid DNA preparations. We demonstrate here that the quantities of LPS typically contaminating DNA preparations can generate a toxicity to primary cells (primary human skin ...
Baker, A., Buschle, M., Cotten, Matt, Saltik, Mediyha, Wagner, Ernst   +4 more
core  

Interactions between Magnetic Nanowires and Living Cells : Uptake, Toxicity and Degradation

, 2011
We report on the uptake, toxicity and degradation of magnetic nanowires by NIH/3T3 mouse fibroblasts. Magnetic nanowires of diameters 200 nm and lengths comprised between 1 {\mu}m and 40 {\mu}m are fabricated by controlled assembly of iron oxide ({\gamma}
Armelle Baeza-Squiban, Auffan M., Berret J.-F., Brunner T. J., Cappallo N., Champion J. A., Chanteau B., Conner S. D., Denizot F., Dietrich Averbeck, Donaldson K., Doshi N., Dumortier H., Florence Niedergang, Fresnais J., Fresnais J., Fresnais J., Fung A. O., Goubault C., Gratton S. E. A., Hallstrom W., Hillaireau H., Hultgren A., Hurst S. J., Hussain S., Hélène Conjeaud, Jacquin M., Jean-François Berret, Johansson F., Kagan V. E., Kim J., Kuimova M. K., Leung K. C. F., Lewinski N., Lutz J.-F. o., Malak Safi, Marie-Alice Guedeau-Boudeville, Massart R., Minhao Yan, Nan A. J., Nicole Boggetto, Niedergang F., Petri-Fink A., Pisanic T. R., Rad A. M., Safi M., Sehgal A., Singh H., Singh N., Song M. M., Tanase M., Virginie Garnier-Thibaud   +51 more
core   +2 more sources

Conclusions of the French Food Safety Agency on the toxicity of bisphenol A [PDF]

, 2011
Since more than 10 years, risk assessment of bisphenol A (BPA) is debated at the international level. In 2008, the U.S. National Toxicology Program (NTP) expressed some concern for adverse effects, at current level of exposure to BPA, on developmental ...
Arnich, Nathalie, Canivenc-Lavier, Marie-Chantal, Coffigny, Hervé, Cravedi, Jean-Pierre, Grob, Konrad, Kolf-Clauw, Martine, Macherey, Anne-Christine, Masset, Dominique, Maximilien, Rémi, Narbonne, Jean-François, Nesslany, Fabrice, Stadler, Jeanne, Tulliez, Jacques   +12 more
core   +2 more sources