Results 101 to 110 of about 780,751 (311)

Perspectives on Testing for Toxic Agents [PDF]

open access: yesEnvironmental Health Perspectives, 1987
A series of observations and comments are made with respect to several areas of toxicology: these are briefly discussed. Some innovative areas receive discussion as representing substantial progress made in the field of toxicology in recent years.
openaire   +3 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Intravenous Single Dose Toxicity of Sweet Bee Venom in Sprague-Dawley Rats

open access: yesJournal of Pharmacopuncture, 2015
Objectives: Anaphylactic shock can be fatal to people who become hypersensitive when bee venom pharmacopuncture (BVP) is used. Thus, sweet bee venom (SBV) was developed to reduce these allergic responses.
Kwang-Ho Lee   +3 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

OF SODIUM NITRITE FOR SPINY-CHEEK CRAYFISH (ORCONECTES LIMOSUS RAF.) THE EFFECT OF CHLORIDE CONTENT IN WATER ON THE TOXICITY

open access: yesKnowledge and Management of Aquatic Ecosystems, 2005
Toxicity of sodium nitrite for the spiny-cheek crayfish (Orconectes limosus) was assessed in relation to the concentration of chlorides diluted in water.
KOZÁK P., MÁCHOVÁ J., POLICAR T.
doaj   +1 more source

Particle size of insecticidal suspensions and their contact toxicity vi. Effect of temperature on relative toxicity

open access: yes, 1957
Two aqueous suspensions, one containing crystals of uniform size and the other containing colloidal particles, were made with each of seven solid contact poisons (two DDT-analogues, DDT, rotenone, 2-bromomercurithiophen, dieldrin and endrin).
Mcintosh, A. H.
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

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