Results 21 to 30 of about 960,647 (282)

Toxicity evaluation of water extract of tissue-cultured Taraxacum formosanum by acute, subacute administration, and Ames test

Electronic Journal of Biotechnology, 2020
Background: Taraxacum species (commonly known as dandelion) used as herbal medicine have been reported to exhibit an antiproliferative effect on hepatoma cells and antitumor activity in non-small-cell lung cancer cells.
Wen-Che Tsai, Hung-Chi Chang, Yi-Han Tseng, Hsin-Yi Yin, Jiunn-Wang Liao, Dinesh Chandra Agrawal, Hsiao-Wei Wen   +6 more
doaj   +1 more source

Tiered Testing Strategies—Acute Local Toxicity [PDF]

ILAR Journal, 2002
More work has been done to develop alternatives to animal use in the areas of eye and skin irritation than in any area other than carcinogenicity. There has long been a belief both in the scientific community and among the public that the development of nonanimal tests in these areas should be simple and straightforward.
openaire   +2 more sources

Acute toxicity test of garlic extract

The Journal of Toxicological Sciences, 1984
The acute toxicity toxicity test of garlic extract was studied in Wistar rats and ddY mice. The LD50 values of garlic extract by P.O., I.P. and S.C. administration were estimated over 30 ml/kg respectively in male and female of both rodents. In 30 ml/kg of I.P.
S, Nakagawa, K, Masamoto, H, Sumiyoshi, H, Harada   +3 more
openaire   +3 more sources

Proton Therapy of Prostate and Pelvic Lymph Nodes for High Risk Prostate Cancer: Acute Toxicity [PDF]

International Journal of Particle Therapy, 2021
Purpose: To assess acute gastrointestinal (GI) and genitourinary (GU) toxicities of intensity-modulated proton therapy (IMPT) targeting the prostate/seminal vesicles and pelvic lymph nodes for prostate cancer.
Richard Choo, MD, David W. Hillman, MS, Thomas Daniels, MD, Carlos Vargas, MD, Jean Claude Rwigema, MD, Kimberly Corbin, MD, Sameer Keole, MD, Sujay Vora, MD, Kenneth Merrell, MD, Bradley Stish, MD, Thomas Pisansky, MD, Brian Davis, MD, PhD, Adam Amundson, William Wong, MD   +13 more
doaj   +1 more source

Acute Toxicity Assay from Seeds and Flesh of Tarap Fruit (Artocarpus odoratissimus Blanco) Ethanolic Extract against Daphnia magna Larvae

Journal of Tropical Pharmacy and Chemistry, 2020
Tarap (Artocarpus odoratissimus Blanco) is one of the plants in the tropics that are consumed by dayak tribe in East Kalimantan. Toxicity tests on seeds and bark have been done but there is no data regarding the acute toxicity of Artocarpus odoratissimus
Crissty Magglin, Ika Fikriah, Khemasili Kosala, Hadi Kuncoro   +3 more
doaj   +1 more source

Ecotoxicological Evaluation of Products Obtained from Technical Cashew Nutshell Liquid (tCNSL) Proposed as Larvicide to Control Aedes aegypti (Diptera: Culicidae)

Ecologies, 2022
The development of new insecticides for vector control that are toxicologically safe and eco-friendly (such as those obtained from industrial by-products) is an important public health concern.
Márcia Ramos Jorge, Felipe Mendes Merey, Bruno do Amaral Crispim, Fábio Kummrow, Alexeia Barufatti, Fabiana Gomes da Silva Dantas, Kelly Mari Pires de Oliveira, Eduardo José de Arruda   +7 more
doaj   +1 more source

Acute and Prolonged Toxicity Tests

Journal of AOAC INTERNATIONAL, 1975
Abstract An answer to the question of whether acute and prolonged toxicity tests are good candidates for standardization is developed by reviewing (1) the factors that are presumed to influence the results of these tests and (2) the collaborative studies that have been reported in the literature.
openaire   +2 more sources

Cytotoxicity and Oral Acute Toxicity Studies of Lantana camara Leaf Extract

Molecules, 2011
Background: The objective of this study was to investigate the toxicity of Lantana camara methanol extract. Methods: In order to evaluate the toxicity of Lantana camara, the acute toxicity of the methanolic extract on adult mice and cytotoxicity test on ...
Badakhshan Mahdi Pour, Sreenivasan Sasidharan, Lachimanan Yoga Latha   +2 more
doaj   +1 more source

Environmental Toxicity Assessment of Organotin Compounds Using the Direct Contact Bioassay – OSTRACODTOXKIT F

Quality in Sport
The aim of the study was to assess the toxicity of organic compound of tin using two tests with Heterocypris incongruens. Chlorides: tributyltin, trimethyltins and triphenyltin were tested by conducted acute (mortality) and chronic toxicity tests ...
Tomasz Szwarc, Piotr Komasara , Paweł Mikołajczak , Mateusz Kałwik , Mateusz Michalak , Hubert Bochenek , Michał Bzoma , Julia Nowakowska , Iga Klepacz   +8 more
doaj   +3 more sources

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source