Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
EURO-ECOLE: Assessment of the Bioavailability and Potential Ecological Effects of Copper in European Surface Waters ; subproject 4: Evaluation and improvement of the ecological relevance of laboratory generated toxicity data [PDF]
, 2002 This report summarizes the acute and chronic toxicity of copper to algae, Daphnia and a few other freshwater species in standard laboratory test water and a wide range of natural surface waters (collected across Europe), with a wide range of pH ...
Bossuyt, Bart +2 more
core
Vaginal Microbicides: Detecting Toxicities in Vivo that Paradoxically Increase Pathogen Transmission [PDF]
, 2006 BACKGROUND: Microbicides must protect against STD pathogens without causing unacceptable toxic effects. Microbicides based on nonoxynol-9 (N9) and other detergents disrupt sperm, HSV and HIV membranes, and these agents are effective contraceptives.
Abusuwwa, Raed +5 more
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Scientia Marina, 2004 The sediment formed by the tailings of an abandoned mine, which discharged into Portmán Bay, Murcia, SE-Spain, was tested to establish a possible gradient of heavy metals.
A. Cesar +3 more
doaj +1 more source
Acute toxicity of cerium oxide, titanium oxide and iron oxide nanoparticles using standardized tests [PDF]
, 2001 In this study, several standard toxicity tests have been performed on selected inorganic nanoparticles. Acute toxicity tests were selected according to their extensive use in toxicological studies and included phytotoxicity using several seeds, Daphnia ...
Ana García +8 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Safety Evaluation of Peony Protein
Shipin gongye ke-jiThis study aimed to assess the safety and toxicity of peony protein and provide a scientific basis for its application in food industry. The safety evaluation included acute oral toxicity tests in mice, as well as 28 d and 90 d oral toxicity tests in ...
Jie LU +5 more
doaj +1 more source
On the possibility of using biological toxicity tests to monitor the work of wastewater treatment plants [PDF]
Archives of Biological Sciences, 2008 The aim of this study was to ascertain the possibility of using biological toxicity tests to monitor influent and effluent wastewaters of wastewater treatment plants.
Zorić Jelena, Simić V., Petrović Ana
doaj +1 more source
Evaluation of engineered nanoparticle toxic effect on wastewater microorganisms: current status and challenges [PDF]
, 2013 The use of engineered nanoparticles (ENPs) in a wide range of products is associated with an increased concern for environmental safety due to their potential toxicological and adverse effects.
Coulon, Frederic +5 more
core +1 more source