Results 151 to 160 of about 15,678,062 (402)

Comparação de métodos para testar a citotoxicidade "in vitro" de materiais biocompatíveis

Revista de Saúde Pública
OBJETIVO: Comparar a sensibilidade do método de difusão em ágar e do método de extração utilizando as linhagens celulares RC-IAL (células fibroblásticas de rim de coelho) e HeLa (células epiteliais de carcinoma do colo do útero humano), na avaliação da ...
Aurea Silveira Cruz, Cristina Adelaide Figueiredo, Tamiko Ichikawa Ikeda, Ana Claudia Egydio Vasconcelos, Jakson Batista Cardoso, Luís Florêncio de Salles-Gomes   +5 more
doaj  

Daphnia magna and Ceriodaphnia dubia Have Similar Sensitivity in Standard Acute and Chronic Toxicity Tests. [PDF]

Environ Toxicol Chem, 2022
Connors KA, Brill JL, Norberg-King T, Barron MG, Carr G, Belanger SE.   +5 more
europepmc   +1 more source

toxicity test

Citation: 'toxicity test' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.16155 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Avoidance behaviour toxicity tests should account for animal gregariousness: a case study on the terrestrial isopod Porcellioscaber. [PDF]

Zookeys, 2022
Zidar P, Fišer Ž.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Application of Fish Embryo Assay Using Zebrafish and Oryzias latipes for Toxicity Testing and Deriving Water Quality Criteria

Applied Sciences
To protect aquatic organisms in ecosystems, each country and continental union has established guidelines for deriving the water quality standards (WQS) of specific substances. These guidelines mandate the use of acute and chronic toxicity data for fish,
Lia Kim, Youn-Joo An
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Synthesis of Organonitrogen Compounds from Eugenol through The Ritter Reaction and The Toxicity Test on Artemia salina Leach.

, 2019
Mohammad Farid Rahman, Ardhya Ayu Pratama   +1 more
openalex   +1 more source

A Critical Review of the Availability, Reliability, and Ecological Relevance of Arctic Species Toxicity Tests for Use in Environmental Risk Assessment. [PDF]

Environ Toxicol Chem, 2022
Eldridge RJ, de Jourdan BP, Hanson ML.
europepmc   +1 more source