Results 41 to 50 of about 15,678,062 (402)
Organoid-based platforms for investigating microplastic-induced human organ toxicity [PDF]
OrganoidMicro- and nano-plastics (MNPs) have emerged as widespread environmental contaminants, raising increasing concerns regarding their potential adverse effects on human health.
Yeongseon Cho, Hong Nam Kim
doaj +1 more source
Journal of Pharmacopuncture, 2015 Objectives: Water-soluble carthami flos (WCF) is a new mixture of Carthami flos (CF) pharmacopuncture. We conducted a 4-week toxicity test of repeated intramuscular injections of WCF in Sprague-Dawley rats.
Yoo-min Choi +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Validation of a method for measuring sperm quality and quantity in reproductive toxicity tests with pair-breeding male fathead minnows (Pimephales promelas) [PDF]
, 2009 This article originally appeared in the ILAR e-Journal. It is reprinted with permission from the ILAR Journal, Institute for Laboratory Animal Research, National Research Council, Washington DC (www.nationalacademies.org/ilar).The fathead minnow ...
Hala, D +3 more
core +1 more source
STopTox: An in Silico Alternative to Animal Testing for Acute Systemic and Topical Toxicity
Environmental Health Perspectives, 2020 Background: Modern chemical toxicology is facing a growing need to Reduce, Refine, and Replace animal tests (Russell 1959) for hazard identification.
Joyce V. B. Borba +13 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale +6 more
wiley +1 more source
ORGANOPHOSPHORUS PESTICIDES TOXICITY ON BRINE SHRIMP, ARTEMIA [PDF]
Journal CleanWAS, 2018 Present investigation discusses the toxic effects of two organophosphorus pesticides (Malathion) and (Glyphosate) on brine shrimp, Artemia in static acute toxicity tests (24hr and 48hr).
Jawahar, A. Jamal, M.S. Arun , B. Akba
doaj +1 more source
Bioavailability of pesticides in freshwater sediments [PDF]
, 2007 In ecological risk assessment standardized sediment toxicity tests are used to predict the hazard of chemicals for sediment-living organisms. Feeding is a prerequisite in these long-term tests to avoid starvation of test organisms.
Åkerblom, Nina
core
Development and validation of Triticum phytobiological method as an alternative procedure for investigating in vivo acute toxicity on mice [PDF]
, 2017 The goal of this study was to validate an alternative method for determining in vivo acute toxicity using vegetal material instead of laboratory animals, starting from the phytobiological method known also as the Triticum technique.
Anghel, Adriana +5 more
core +4 more sources
In silico toxicology: computational methods for the prediction of chemical toxicity
Wiley Interdisciplinary Reviews. Computational Molecular Science, 2016 Determining the toxicity of chemicals is necessary to identify their harmful effects on humans, animals, plants, or the environment. It is also one of the main steps in drug design.
A. Raies, V. Bajic
semanticscholar +1 more source