Results 61 to 70 of about 410,071 (262)
The study of an acute toxicity of extracts from Veronica teucrium L. and from Veronica longifolia L.
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018 The aim of our work were to study the acute toxicity of extracts obtained from herb, leaves, flowers of V. teucrium L. and from herb of V. longifolia L. Materials and methods.
А. Р. Osmachko +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Compliance to HIV treatment monitoring guidelines can reduce laboratory costs
Southern African Journal of HIV Medicine, 2016 Background: Panel tests are a predetermined group of tests commonly requested together to provide a comprehensive and conclusive diagnosis, for example, liver function test (LFT).
Naseem Cassim +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Journal of Tropical Pharmacy and ChemistryPyrazoline is an alkaloid compound which has various biological activities such as antibacterial, antifungal, antitumor and anticancer. The compound N-carbotioamide-3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl)pyrazoline was successfully ...
Muhammad Irfan +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Inhibitory Effects of Two Kinds of Microplastics on the Growth of Skeletonema costatum
Haiyang Kaifa yu guanliAs a new pollutant, microplastics may have an impact on the growth and photosynthesis of marine phytoplankton. In order to study the growth inhibitory effect of microplastics on the Skeletonema costatum in marine phytoplankton, the paper adopts light ...
YU Mingru, GUO Hui, WU Jianping
doaj
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2022 Background and Aim The high use of pesticides has increased the concern about its possible harm to individual and environment health. Chronic exposure to pesticides has serious effects on different body organs even before the onset of clinical symptoms ...
Mir Saeed Attarchi +7 more
doaj
Potential toxicity of Schisandra chinensis to water environment: acute toxicity tests with water crustaceans. [PDF]
Environ Sci Pollut Res Int, 2023 Valíčková J +5 more
europepmc +1 more source