Results 81 to 90 of about 3,771,189 (312)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
PSYNDEX Tests Review für FMT - FELDMARKIERUNGSTEST
, 1986 This is a PSYNDEX Tests Review of FMT - FELDMARKIERUNGSTEST. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Plab, Josef
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
PSYNDEX Tests Review für KT - KRAMER-TEST
, 1982 This is a PSYNDEX Tests Review of KT - KRAMER-TEST. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Kramer, Josefine
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Determining safety of betacarboclomet cream in epidermal delivery to the body of animals
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015 Aim. The article is devoted to safety determining of newly developed drug as one of the important stages of preclinical evaluation in the organization of industrial manufacturing. Methods and results.
G. M. Voytenko +3 more
doaj +1 more source
PSYNDEX Tests Review für MDT 7 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 7. SCHULSTUFE
, 1983 This is a PSYNDEX Tests Review of MDT 7 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 7. SCHULSTUFE. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Lukesch, Helmut
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A Guidance Manual for the Toxicity Assessment of Traditional Herbal Medicines
Natural Product Communications, 2016 Herbal remedies have been used for thousands of years in worldwide traditional medicines for their potential health benefits. Although they are generally presumed safe unless a significant risk has been identified in humans, increasing number of case ...
Ahmet Aydιn +2 more
doaj +1 more source