Results 91 to 100 of about 784,142 (261)

Biodegradability standards for carrier bags and plastic films in aquatic environments: a critical review [PDF]

open access: yes, 2018
Plastic litter is encountered in aquatic ecosystems across the globe, including polar environments and the deep sea. To mitigate the adverse societal and ecological impacts of this waste, there has been debate on whether ‘biodegradable’ materials should ...
Ardisson GB   +33 more
core   +4 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Determining safety of betacarboclomet cream in epidermal delivery to the body of animals

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. The article is devoted to safety determining of newly developed drug as one of the important stages of preclinical evaluation in the organization of industrial manufacturing. Methods and results.
G. M. Voytenko   +3 more
doaj   +1 more source

Fire resistivity and toxicity studies of candidate aircraft passenger seat materials [PDF]

open access: yes
Fire resistivity studies were conducted on a wide range of candidate nonmetallic materials being considered for the construction of improved fire resistant aircraft passenger seats.
Fewell, L. L.   +2 more
core   +1 more source

Global Requirements of Chitosan for Medical and Food Applications [PDF]

open access: yes, 2011
Chitosan is a biopolymer obtained by deacetylation of chitin which widely distribute in nature and biologically safe. This polymer exhibits several favor properties such as biodegradability, low toxicity and ability to form film hydrogel. Chitosan offers
Savitri, Emma   +2 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Compliance to HIV treatment monitoring guidelines can reduce laboratory costs

open access: yesSouthern African Journal of HIV Medicine, 2016
Background: Panel tests are a predetermined group of tests commonly requested together to provide a comprehensive and conclusive diagnosis, for example, liver function test (LFT).
Naseem Cassim   +3 more
doaj   +1 more source

Fish and amphibians as test organisms for evaluation of effects caused by chemicals [PDF]

open access: yes, 2007
A large number of chemicals can contaminate aquatic environments and therefore be exposed to fish and amphibians during their sensitive stages of development.
Carlsson, Gunnar
core  

Experimental evolution reveals high insecticide tolerance in Daphnia inhabiting farmland ponds [PDF]

open access: yes, 2015
Exposure of nontarget populations to agricultural chemicals is an important aspect of global change. We quantified the capacity of natural Daphnia magna populations to locally adapt to insecticide exposure through a selection experiment involving ...
Agra   +36 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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