Results 91 to 100 of about 435,111 (310)

Understanding the causes of toxicity in treated landfill leachate through whole eefluent testing [PDF]

, 2010
Landfill leachate is collected and treated before discharge to protect the environment from a potential toxic cocktail of substances. In the U.K. biological treatment is the favourite technology for rendering landfill leachate safe due its simple ...
Thomas, David J. L.
core  

Synthesis and Toxicity Tests of N-Carbothioamide-3-(2,4- Dichlorophenyl)-5-(4-Hydroxy-3-Methoxyphenyl)Pyrazolineo

Journal of Tropical Pharmacy and Chemistry
Pyrazoline is an alkaloid compound which has various biological activities such as antibacterial, antifungal, antitumor and anticancer. The compound N-carbotioamide-3-(2,4-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl)pyrazoline was successfully ...
Muhammad Irfan, Lisna Meylina, Agung Ramadhani, Rolan Rusli   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical and Biochemical Characteristics of Male Workers in a Pesticide Production Factory in Guilan Province, Iran

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2022
Background and Aim The high use of pesticides has increased the concern about its possible harm to individual and environment health. Chronic exposure to pesticides has serious effects on different body organs even before the onset of clinical symptoms ...
Mir Saeed Attarchi, Fatemeh Nejatifar, Hamid Mohammadi Kojidi, Zahra Atrkar Roushan, Niloofar Faraji, Maryam Joshan, Fatemeh Rahattalab, Roholah Amini   +7 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Use of microtox tests for screening industrial wastewater toxicity

, 1996
Conventional parameters such as chemical oxygen demand and suspended solids may not detect toxic compounds present in a variety of industrial wastewaters and treated wastes.
Oliver J. Hao, Shin Chien-Jen, Lin Cheng-Fang, Jeng Fu-Tien, Chen Zen-Chyuan   +4 more
core   +1 more source

Inhibitory Effects of Two Kinds of Microplastics on the Growth of Skeletonema costatum

Haiyang Kaifa yu guanli
As a new pollutant, microplastics may have an impact on the growth and photosynthesis of marine phytoplankton. In order to study the growth inhibitory effect of microplastics on the Skeletonema costatum in marine phytoplankton, the paper adopts light ...
YU Mingru, GUO Hui, WU Jianping
doaj  

Potential toxicity of Schisandra chinensis to water environment: acute toxicity tests with water crustaceans. [PDF]

Environ Sci Pollut Res Int, 2023
Valíčková J, Zezulka Š, Maršálková E, Kotlík J, Maršálek B, Opatřilová R.   +5 more
europepmc   +1 more source

Perspectives on Testing for Toxic Agents [PDF]

Environmental Health Perspectives, 1987
A series of observations and comments are made with respect to several areas of toxicology: these are briefly discussed. Some innovative areas receive discussion as representing substantial progress made in the field of toxicology in recent years.
openaire   +3 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source