Results 101 to 110 of about 9,004 (219)

A Systematic Review of the Toxicokinetics of Micro- and Nanoplastics in Mammals Following Digestive Exposure

Applied Sciences
The high production of plastic, along with its biostability and poorly managed recycling, has led to its widespread presence in the environment. Pollution from microplastics (particles smaller than 5 mm) and nanoplastics (particles smaller than 1 μm ...
Raluca Paula Popa, Alexandru Flaviu Tabaran   +1 more
doaj   +1 more source

Clinical Profiles and Therapeutic Interventions in Occult Paraquat Poisoning: A Comparative Report of Two Cases [PDF]

Clin Case Rep
ABSTRACT Delayed diagnosis invariably worsens outcomes in occult paraquat poisoning regardless of exposure route. Implement early urinary screening for suspected cases. Tailor antioxidant and anti‐fibrotic timing to toxicokinetic patterns to mitigate irreversible pulmonary damage.
Zhao M, Zhou S, Zhang Y, Yuan E, Peng M, Gao Y.   +5 more
europepmc   +2 more sources

Role of glutathione and cysteine in acrylamide metabolism during in vitro and in vivo digestion

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 5012-5020, June 2026.
Abstract Background Acrylamide, a probable human carcinogen found in thermally processed potato products, is reactive towards amino and thiol compounds. This reactivity suggests acrylamide might react with them in the gastrointestinal tract resulting in mitigation of associated risk with acrylamide.
Burçe Ataç Mogol, Choong‐In Yun, Aytül Hamzalıoğlu, Selin Çakmak, Yeşim Şensoy, Nazmiye Çitler, Eunjung Lee, Shin Young Park, Junwon Byun, Young‐Jun Kim, Sanguine Byun, Vural Gökmen   +11 more
wiley   +1 more source

Efficient in vitro lipolysis: a tool to study the toxicokinetics of lipophilic compounds

, 2011
Efficient in vitro lipolysis: a tool to study the toxicokinetics of lipophilic ...
ICAT 2011, International Conference on Adipose Tissue, Louis, Caroline, Larondelle, Yvan, Bourez, Sophie, Van den Daelen, Carine, Debier, Cathy   +5 more
core  

Therapeutic drug monitoring of methotrexate after its administration in high doses for osteosarcoma treatment in children

Фармакокинетика и Фармакодинамика, 2020
In children oncology high doses of methotrexate (HD Mtx) use for treatment of osteosarcoma, acute lymphoblastic leukemia and many others tumors. Due to high intra- and interindividual Mtx pharmacokinetic variability it is essential perform monitoring its
A. M. Strizhevskaya, E. G. Golovnya, I. S. Kuleshova, A. Z. Dzampaeva, V. N. Baykova   +4 more
doaj  

Preclinical Efficacy and Safety Study of a Novel Dermal Fibroblast Modulating Drug, SLI‐F06, in Cutaneous Wound Healing

MedComm, Volume 7, Issue 6, June 2026.
A novel, chemically synthesized fibromodulin (FMOD)‐derived peptide, SLI‐F06, has been developed to significantly improve scar appearance, tensile strength, and histological outcomes among multiple preclinical animal models. Demonstrating no genotoxicity or systemic/local toxicity, SLI‐F06 has received United States Food and Drug Administration ...
Zhong Zheng, Pin Ha, Chenshuang Li, Grace Xinlian Chang, Wenlu Jiang, Xiaoxiao Pang, Zhaohan Zeng, Elisabeth Leeflang, Kang Ting, Chia Soo   +9 more
wiley   +1 more source

Oral Exposure to Chlorella sorokiniana Detoxifies Deoxynivalenol, Ochratoxin A, and Fumonisin B1 In Vitro and In Vivo

Toxins
Mycotoxins are synthesized by various fungal species and are known to exert toxic effects on vertebrates and other animals, even at low concentrations. However, the current countermeasure for mycotoxin contamination is random inspection of samples prior ...
Hiroki Yamaguchi, Mana Ando, Chiharu Ohira, Tensei Magami, Mao Kaneki, Kazutoshi Sugita, Taro Ogawa, Ayaka Nakashima, Tomoki Fukuyama   +8 more
doaj   +1 more source

Past Pollution Can Shape Future Climatic Vulnerability: Fungicide Exposure Alters Detritivore Performance During Heatwaves and Recovery

Freshwater Biology, Volume 71, Issue 6, June 2026.
ABSTRACT Natural populations are increasingly exposed to multiple stressors, such as chemical pollution and climate‐change‐driven heatwaves. While it has become clear that we need to account for stressor interactions, it is less well understood how sequential exposure to different stressors influences organismal responses as well as their potential for
Akshay Mohan, Blake Matthews, Katja Räsänen   +2 more
wiley   +1 more source

Update of the risk assessment on dioxins and dioxin‐like PCBs in feed and food

EFSA Journal, Volume 24, Issue 6, June 2026.
Abstract The European Commission asked EFSA to update its 2018 risk assessment on polychlorinated dibenzo‐p‐dioxins and dibenzofurans (PCDD/Fs) and dioxin‐like polychlorinated biphenyls (DL‐PCBs) in feed and food, based on the 2022 WHO Toxic Equivalency Factors (WHO2022‐TEFs).
EFSA Panel on Contaminants in the Food Chain (CONTAM Panel), Helle Katrine Knutsen, Agneta Åkesson, Vasileios Bampidis, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Gisela Degen, Antonio Hernández‐Jerez, Tim Hofer, Christer Hogstrand, Stefano Landi, Jean‐Charles Leblanc, Kyriaki Machera, Evangelia Ntzani, Isabelle P. Oswald, Guido Rychen, Salomon Sand, Katharina Vejdovszky, Barbara Viviani, Jesús del Mazo, Andy Hart, Dieter Schrenk, José Cortiñas Abrahantes, Luisa Ramos Bordajandi, Francesca Riolo, Tuuli Tauriainen, Ron Hoogenboom   +27 more
wiley   +1 more source

Correction to “Tissue-Specific Toxicokinetics of Aqueous Radium-226 in an Estuarine Mussel, Geukensia demissa”

Correction to “Tissue-Specific Toxicokinetics of Aqueous Radium-226 in an Estuarine Mussel, Geukensia ...
Annelise K. Gonzales (14641390), Nicole E. Martinez (9119716), Bryanna D. Wattier (14641393), Brian A. Powell (1407076), Robert P. Dunn (7057016), Sarah E. Donaher (10684602)   +5 more
core   +1 more source