Results 171 to 180 of about 9,004 (219)

Preclinical Safety Evaluation of BB106, a Novel Ketamine-Sulfobutylether-Beta-Cyclodextrin Salt, Following Subcutaneous Administration in Rats and Göttingen Minipigs. [PDF]

Int J Toxicol
Ramot Y, Andreini I, Sacco G, Becker J, Bruhn K, Manno RA, Nyska A.   +6 more
europepmc   +1 more source

Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series. [PDF]

Front Pharmacol
Cafaro A, Pigliasco F, Barco S, Negro I, Piccotti E, Manfredini L, Mahameed S, Bandettini R, Debbia C, Mattioli F, Cangemi G.   +10 more
europepmc   +1 more source

Toxicokinetics

, 2021
Presentation as guest of class of Dr. Julia Rager at UNC-CH on September 13-15, 2021Science Inventory, CCTE products: https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any&dateBeginPublishedPresented=07/01/2017& ...
Jesús Molpeceres, María de los Ángeles, María del Rosario Aberturas   +2 more
core   +3 more sources

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Toxicokinetics

Food Additives and Contaminants, 2000
The toxicokinetic determinants of dioxin and related chemicals depend on three major properties: lipophilicity, metabolism, and binding to CYP1A2 in the liver. The induction of CYP1A2 is partially under the control of the aryl hydrocarbon receptor (AhR).
van Birgelen, A.P.J.M., van den Berg, M.
openaire   +4 more sources

The Toxicokinetics and Metabolism of Polychlorinated Dibenzo-p-Dioxins (PCDDs) and Dibenzofurans (PCDFs) and Their Relevance for Toxicity

Critical Reviews in Toxicology, 1994
74 p.This article reviews the present state of the art regarding the toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). The absorption, body distribution, and metabolism can vary greatly between species
Martin Van Den Berg, Joost De Jongh, H Poiger   +2 more
exaly   +1 more source

ALUMINUM TOXICOKINETICS

Journal of Toxicology and Environmental Health, 1996
In this study of the toxicokinetics of aluminum we have examined some of the fundamental issues that currently define our understanding of the toxicology of aluminum in humans. There is a vast literature on this subject, and it was not our aim to review this literature but to use it to develop our understanding of the toxicokinetics of aluminum and to ...
C, Exley, E, Burgess, J P, Day, E H, Jeffery, S, Melethil, R A, Yokel   +5 more
openaire   +2 more sources

Interactions of pesticides with membrane drug transporters: implications for toxicokinetics and toxicity

Expert Opinion on Drug Metabolism and Toxicology, 2018
International audienceDrug transporters are now recognized as major actors of pharmacokinetics. They are also likely implicated in toxicokinetics and toxicology of environmental pollutants, notably pesticides, to which humans are widely exposed and which
Arnaud Bruyere, Astrid Bacle, Marc Le Vee   +2 more
exaly   +2 more sources

Toxicokinetics

1978
The absorption, distribution and elimination of toxic compounds can be described by means of kinetic parameters such as used in pharmacology. Administration of toxic doses may lead to changes in some of the parameters. The toxic effect may further influence the known parameters of some test substances.
O, Karlog, P, Nielsen, F, Rasmussen
openaire   +2 more sources

Pharmacology of carbon nanotubes: Toxicokinetics, excretion and tissue accumulation

Advanced Drug Delivery Reviews, 2013
Carbon nanotubes (CNT) are increasingly being investigated for their use in biomedical applications and nanomedicine. An emergent need for the understanding of their in vivo biodistribution and pharmacokinetics is therefore needed to establish the ...
Hanene Ali-Boucetta, Kostas Kostarelos
exaly   +2 more sources

Toxicokinetics of the nerve agent (±)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration

Toxicology and Applied Pharmacology, 2003
In continuation of our investigations on the toxicokinetics of the volatile nerve agents C(±)P(±)-soman and (±)-sarin, we now report on the toxicokinetics of the rather nonvolatile agent (±)-VX.
Marcel J Van Der Schans, Jan P Langenberg, H P Benschop   +2 more
exaly   +1 more source