Results 41 to 50 of about 7,286 (176)

Nonpolar and Polar Lipids Composition in Recombinant Chinese Hamster Ovary Cells by Nile Red Staining Flow Cytometry

European Journal of Lipid Science and Technology, Volume 128, Issue 9, September 2026.
Cellular lipid composition is a dynamic process. Understanding it is important to improve recombinant protein production. Molecules with solvatochromic properties allow the determination of lipids of different polarities by flow cytometry and offer a useful method for monitoring lipids during different phases of cell growth in bioprocesses.
Francisco E. López‐Salas, Enrique García‐Hernández, Francisco Gasteazoro, Emiliano Balderas‐Ramírez, Octavio T. Ramírez, Georgina I. López‐Cortés, Helgi Jung‐Cook, Emilio Rojas, Mauricio A. Trujillo‑Roldán, Norma A. Valdez‑Cruz   +9 more
wiley   +1 more source

DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents

Anais da Academia Brasileira de Ciências, 2016
The aim of this study was to evaluate potential DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents, mainly xylene.
TATIANE DE AQUINO, FERNANDA F. ZENKNER, JOEL H. ELLWANGER, DANIEL PRÁ, ALEXANDRE RIEGER   +4 more
doaj   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

Toxicologia dos cosméticos [PDF]

, 2007
Apesar de não ser desejável, os produtos cosméticos podem ocasionar alguns efeitos adversos ao usuário. Tais efeitos podem ser decorrentes de fatores individuais como também pelo uso inadequado. Logo, a avaliação de segurança deve preceder a colocação do produto cosmético no mercado.
Chorilli, Marlus, Scarpa, Maria Virgínia, Leonardi, Gislaine Ricci, Franco, Yoko Oshima   +3 more
openaire   +1 more source

Toxicologia: uma abordagem multidisciplinar – Volume I

, 2021
Desde os períodos mais remotos, nas civilizações primitivas, substâncias presentes na natureza eram utilizadas para fins diversos, como a caça e extermínio de inimigos. Com a evolução da humanidade, muitos esforços têm sido feitos para o avanço no conhecimento acerca do uso seguro de substâncias presentes em diversos contextos da vida, através da ...
openaire   +1 more source

Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana

Plant, Cell &Environment, Volume 49, Issue 9, Page 7168-7190, September 2026.
ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros, Asier Largo‐Gosens, Cristina Úbeda, Cristina Hernández‐Fernández, Alba Manga‐Robles, Diego Rebaque, Antonio Encina, Hugo Mélida   +7 more
wiley   +1 more source

Classificação de resíduos sólidos industriais com base em testes ecotoxicológicos utilizando Daphnia magna: uma alternativa

Biotemas, 2005
O tratamento e a disposição final adequada dos resíduos sólidos industriais dependem de sua classificação em classe I ou II. Esta classificação é proposta pela NBR 10.004, contudo, é complexa e demanda tempo.
Letícia Flohr, Débora Monteiro Brentano, Cátia Regina Silva de Carvalho-Pinto, Vanessa Guimarães Machado, William Gerson Matias   +4 more
doaj  

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, Volume 13, Issue 47, 24 August 2026.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Possibilidades terapêuticas e risco toxicológico de Jatropha gossypiifolia L.: uma revisão narrativa Therapeutic possibilities and toxicological risk of Jatropha gossypiifolia L.: a narrative review

Revista Brasileira de Plantas Medicinais, 2010
A espécie Jatropha gossypiifolia L. (Euphorbiaceae), popularmente conhecida como pião-roxo, entre tantos outros nomes, é um bom exemplo do tênue limiar que separa o efeito terapêutico do tóxico.
S.R. Mariz, A.C.R. Borges, M.F.F. Melo-Diniz, I.A. Medeiros   +3 more
doaj   +1 more source