Results 51 to 60 of about 4,914 (198)

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara   +4 more
wiley   +1 more source

PROPRIEDADES FARMACOLÓGICAS E TOXICOLOGIA DO ÓLEO ESSENCIAL DE HYPTIS MARTIUSII BENTH. (CIDREIRA-BRAVA) E DE SEU COMPOSTO MAJORITÁRIO 1,8-CINEOL: UMA REVISÃO

open access: yesRevista Interfaces Saúde Humanas e Tecnologia, 2020
Hyptis martiusii Benth. (Lamiaceae), popularmente conhecida como cidreira-do-mato ou cidreira-brava, e encontrada em abundância no nordeste do Brasil. Trata-se de uma especie potencialmente fornecedora de oleos essenciais, compostos orgânicos volateis ...
G. F. R. Caldas   +6 more
semanticscholar   +1 more source

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira   +2 more
wiley   +1 more source

Intoxicação cúprica em ovinos via concentrado e sal mineral: Relato de caso

open access: yesPubvet, 2018
O presente relato teve por objetivo descrever o quadro clínico-patológico da intoxicação por cobre em ovinos. A ocorrência mais comum de intoxicação por cobre está relacionada à ingestão de concentrado e suplementos minerais destinados a bovinos.
Daniel Lúcio do Nascimento   +5 more
doaj   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa   +9 more
wiley   +1 more source

DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents

open access: yesAnais da Academia Brasileira de Ciências, 2016
The aim of this study was to evaluate potential DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents, mainly xylene.
TATIANE DE AQUINO   +4 more
doaj   +1 more source

Oxytetracycline as an otolith chemical marker in Atlantic bluefin tuna (Thunnus thynnus): Technical feasibility in culture

open access: yesJournal of Fish Biology, EarlyView.
Abstract Reliable discrimination between wild and cultured fish is essential for traceability in aquaculture. This study reports the first successful application of intramuscular oxytetracycline (OTC) injection for otolith marking in juveniles of Atlantic bluefin tuna (Thunnus thynnus).
Inma Salvat‐Leal   +3 more
wiley   +1 more source

A toxicologia in silico no desenvolvimento de fármacos: um caminho ético e inovador na avaliação de segurança

open access: yesBIOINFO
A toxicologia desempenha um papel essencial no desenvolvimento de fármacos, e precisa estar alinhada às exigências regulatórias. As ferramentas computacionais representam um avanço na toxicologia contemporânea ao fornecer novos caminhos na previsão de ...
Anne Josiele Lima Vital   +5 more
semanticscholar   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle   +12 more
wiley   +1 more source

Classificação de resíduos sólidos industriais com base em testes ecotoxicológicos utilizando Daphnia magna: uma alternativa

open access: yesBiotemas, 2005
O tratamento e a disposição final adequada dos resíduos sólidos industriais dependem de sua classificação em classe I ou II. Esta classificação é proposta pela NBR 10.004, contudo, é complexa e demanda tempo.
Letícia Flohr   +4 more
doaj  

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