Results 91 to 100 of about 22,157,959 (291)

Extractables and Leachables in Pharmaceutical Products: Potential Adverse Effects and Toxicological Risk Assessment

open access: yes
During production, storage, and administration, drug products (and their intermediates) are in contact with many different types of materials, which include manufacturing components, container closure systems, and administration materials; therefore ...
Marija Dolenc   +9 more
core   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

open access: yesAdvanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan   +10 more
wiley   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan   +15 more
wiley   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

open access: yesAdvanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An   +8 more
wiley   +1 more source

The relationship of toxicological, demographic and forensic features of suicides other than overdose

open access: yes, 2009
Ciljevi istraživanja: Ispitati, utvrditi i analizirati toksikološke, demografske i sudsko-medicinske značajke samoubojstava koja nisu povezana s predoziranjem, kako bi se dokazalo ili opovrgnulo postojanje njihova međusobnog odnosa, te ispitati značaj ...
Čoklo, Miran
core   +1 more source

The Role of Autophagy in Cancer Evolution and Prognosis, Highlighting Its Role in PCa and Its Interaction with Apoptosis and Epigenetic Regulation by miRNAs

open access: yesMedical Sciences
Background: Autophagy is a process that diversely impacts the stages of both tumor initiation and progression. Elucidating the molecular mechanisms underlying autophagy and its role in tumorigenesis is a key component of anticancer strategies in both ...
Magdalena Kurkiewicz   +3 more
doaj   +1 more source

On the implementation of toxicological assessment at SCA Personal Care

open access: yes, 2007
In this master thesis the possibility and relevance of implementation of toxicological assessment are examined. At SCA Personal Care life cycle assessment (LCA) is used for environmental assessment of new design in the product development process. Now it
Niklasson, Klara
core  

In silico analysis of toxicological properties of EPIIS predicted using the pkCSM methodology.

open access: yes, 2018
In silico analysis of toxicological properties of EPIIS predicted using the pkCSM methodology.
Maria A. Guimarães (427167)   +17 more
core   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

open access: yesAdvanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou   +11 more
wiley   +1 more source

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