Results 91 to 100 of about 839,197 (349)

Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5) : saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched‐chain carboxylic acids from chemical group 5 [PDF]

, 2017
Acknowledgements: The Panel wishes to thank the members of the Working Group on Flavourings: Ulla Beckman Sundh, Leon Brimer, Karl-Heinz Engel, Paul Fowler, Rainer Gürtler, Trine Husøy, Wim Mennes and Gerard Mulder for the preparatory work on this ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Mosesso, Pasquale, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +25 more
core   +2 more sources

Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies.

Basic & Clinical Pharmacology & Toxicology, 2018
Inconsistencies in the reproducibility of research findings are of pertinent concern throughout the scientific community. Initially addressed in preclinical biomedicine studies [1, 2], the discussion has expanded to fields outside the natural sciences ...
P. Tveden-Nyborg, T. Bergmann, J. Lykkesfeldt   +2 more
semanticscholar   +1 more source

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]

, 2010
Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M., Bhattacharjee, S., Evers, N.M., Haan, L.H.J., de, Jiang, X., Marcelis, A.T.M., Rietjens, I.M.C.M., Zuilhof, H.   +7 more
core   +2 more sources

Extracellular‐Matrix‐Based Materials from Decellularized Tissue: Opportunities, Challenges, and Future Directions in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Extracellular matrix‐based materials derived from decellularized tissue (dECM) harness the tissue's native bioactivity to guide repair and regeneration across diverse clinical applications. This perspective highlights clinical uses of dECM biomaterials and advances in fabrication methods such as electrospinning and 3D printing.
Madeline Laude, Vasiliki Kolliopoulos, Antonios G. Mikos, Lisa J. White, Elizabeth Cosgriff‐Hernandez   +4 more
wiley   +1 more source

Application of high-content analysis in food toxicology

Zhongguo shipin weisheng zazhi
High content analysis combines automated microscopy and quantitative image analysis to visualize in vitro models for multi-parameter analysis， which has the advantages of high efficiency， rapidity and multi-targeting， and it has been applied in the field
QIANG Yuwei, YANG Miao, LI Yufeng
doaj   +1 more source

Network toxicology: A new science [PDF]

Computational Ecology and Software, 2016
Network toxicology is related to network biology. Based on my previous study (Zhang, 2016c), in present article I further outlined and defined the aims, scope, theory and methodology of network toxicology.
WenJun Zhang
doaj  

Sensing of EGTA Mediated Barrier Tissue Disruption with an Organic Transistor

Biosensors, 2013
Barrier tissue protects the body against external factors by restricting the passage of molecules. The gastrointestinal epithelium is an example of barrier tissue with the primary purpose of allowing the passage of ions and nutrients, while restricting ...
Scherrine Tria, Leslie H. Jimison, Adel Hama, Manuelle Bongo, Róisín M. Owens   +4 more
doaj   +1 more source

Harvesting the Promise of AOPs: An assessment and recommendations [PDF]

, 2018
The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals.
Ankley, Gerald T., Carusi, Annamaria, Davies, Mark R., De Grandis, Giovanni De, Escher, Beate I., Hodges, Geoff, Wheelan, Maurice, Willet, Catherine, Y. Leung, Kenneth M.   +8 more
core   +3 more sources

Air–Liquid Interface In Vitro Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations

Applied In Vitro Toxicology, 2018
In vitro air–liquid interface (ALI) cell culture models can potentially be used to assess inhalation toxicology endpoints and are usually considered, in terms of relevancy, between classic (i.e., submerged) in vitro models and animal-based models.
G. Lacroix, W. Koch, D. Ritter, A. Gutleb, S. Larsen, T. Loret, Filippo Zanetti, S. Constant, Savvina Chortarea, B. Rothen‐Rutishauser, P. Hiemstra, E. Fréjafon, Philippe Hubert, L. Gribaldo, P. Kearns, Jean-Marc Aublant, S. Diabaté, C. Weiss, Anne C. D. de Groot, I. Kooter   +19 more
semanticscholar   +1 more source