Results 21 to 30 of about 706,933 (359)

Nephroprotective Effect of L-Carvone on a Mouse Model of LPS-Induced Sepsis-Associated Renal Injury via Regulation of TLR4/NF-κB/AP-1/IRF-3 and Nrf2/iNOS Molecular Signaling Cascades

Journal of Taibah University Medical Sciences
الملخص: أهداف البحث: يُعد الإنتان من الحالات السريرية الخطيرة الناتجة عن استجابة مناعية غير منضبطة، تؤدي إلى التهاب جهازي واسع النطاق وإصابة متعددة للأعضاء، وتُعد الكلى من أكثر الأعضاء تأثرًا.
Saja M. Shareef, PhD (Pharmacology and Toxicology), Sarmed H. Kathem, PhD (Pharmacology and Toxicology), Hayder Ridha-Salman, PhD (Pharmacology)   +2 more
doaj   +1 more source

Semiconductor Electronic Label-Free Assay for Predictive Toxicology. [PDF]

, 2016
While animal experimentations have spearheaded numerous breakthroughs in biomedicine, they also have spawned many logistical concerns in providing toxicity screening for copious new materials. Their prioritization is premised on performing cellular-level
Chui, Chi On, Ji, Zhaoxia, Mao, Yufei, Meng, Huan, Shin, Kyeong-Sik, Wang, Xiang   +5 more
core   +2 more sources

Proteomics for systems toxicology

Computational and Structural Biotechnology Journal, 2014
Current toxicology studies frequently lack measurements at molecular resolution to enable a more mechanism-based and predictive toxicological assessment.
Bjoern Titz, Ashraf Elamin, Florian Martin, Thomas Schneider, Sophie Dijon, Nikolai V. Ivanov, Julia Hoeng, Manuel C. Peitsch   +7 more
doaj   +1 more source

Current advances on the phytochemical composition, pharmacologic effects, toxicology, and product development of Phyllanthi Fructus

Frontiers in Pharmacology, 2022
Phyllanthi Fructus (PF), the edible fruits of Phyllanthus emblica L., serves as an important resource for some health products, foods and drugs due to its high safety and sufficient nutritional value.
Xiaoyu Yan, Qiuju Li, Qiuju Li, Lin Jing, Shuangyue Wu, Wei Duan, Yan Chen, Yan Chen, Dayi Chen, Xiaoqi Pan, Xiaoqi Pan   +10 more
doaj   +1 more source

An Undergraduate Toxicology Seminar Focusing on Ethical Reasoning and Communication Skill Development [PDF]

, 2020
The development of an undergraduate major in toxicology at Nazareth College provided the opportunity to develop a one-credit Principles of Toxicology Seminar designed to address ethical reasoning skills and communication (both oral and written), areas ...
Zamule, Stephanie
core  

Alternaria in food: Ecophysiology, mycotoxin production and toxicology [PDF]

, 2015
Alternaria species are common saprophytes or pathogens of a wide range of plants pre- and post-harvest. This review considers the relative importance of Alternaria species, their ecology, competitiveness, production of mycotoxins and the prevalence of ...
Lee, Hyang Burm, Magan, Naresh, Patriarca, Andrea   +2 more
core   +2 more sources

Network toxicology and its application in studying exogenous chemical toxicity

环境与职业医学
With the continuous development of society, a large number of new chemicals are continuously emerging, which presents a challenge to current risk assessment and safety management of chemicals.
Yanli LIN, Zehua TAO, Zhao XIAO, Chenxu HU, Bobo YANG, Ya WANG, Rongzhu LU   +6 more
doaj   +1 more source

Simultaneous Measurement and Distribution Analysis of Urinary Nicotine, Cotinine, Trans-3′-Hydroxycotinine, Nornicotine, Anabasine, and Total Nicotine Equivalents in a Large Korean Population

Molecules, 2023
Measurement of multiple nicotine metabolites and total nicotine equivalents (TNE) might be a more reliable strategy for tobacco exposure verification than measuring single urinary cotinine alone.
Hyun-Seung Lee, Mi-Ryung Chun, Soo-Youn Lee   +2 more
doaj   +1 more source

A Multi-Level Analysis of World Scientific Output in Pharmacology [PDF]

, 2012
The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database.
Olmeda-Gómez, Carlos, Ovalle-Perandones, María-Antonia, Perianes-Rodríguez, Antonio   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source