PerFluoroAlkyl Substances (PFAS) are responsible of major and persistent environmental pollution worldwide. This work demonstrates an ultra‐sensitive sensor for PFAS based on an organic transistor whose gate is functionalized with a binary self‐assembled monolayer containing a perfluorinated molecule.
Rian Zanotti+8 more
wiley +1 more source
Antidote application: an educational system for treatment of common toxin overdose [PDF]
Poisonings account for almost 1% of emergency room visits each year. Time is a critical factor in dealing with a toxicologic emergency. Delay in dispensing the first antidote dose can lead to life-threatening sequelae.
Brusic, V.+4 more
core
Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]
Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M.+7 more
core +2 more sources
Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah+3 more
wiley +1 more source
Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies.
Inconsistencies in the reproducibility of research findings are of pertinent concern throughout the scientific community. Initially addressed in preclinical biomedicine studies [1, 2], the discussion has expanded to fields outside the natural sciences ...
P. Tveden-Nyborg+2 more
semanticscholar +1 more source
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail+3 more
wiley +1 more source
Introducing Toxicology into the Biochemistry Curricula: Using Cytochrome c (Cytc) Functionalities as a Model [PDF]
The electron transport chain (ETC) is a keystone topic of all biochemistry courses at the undergraduate level. Many ETC components, especially cytochrome c (Cytc), are also important to the field of toxicology. Unfortunately, many primarily undergraduate
Borland, Michael
core
Survivors Speak: A Qualitative Analysis of Motivational Factors Influencing Breast Cancer Survivors’ Participation in a Sprint Distance Triathlon [PDF]
Aims and Objectives To examine motivational factors influencing breast cancer survivors to participate in triathlon training, complete a triathlon and maintain an exercise thereafter.
Ng, Alexander V.+4 more
core +2 more sources
Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety
Pyrrolizidine alkaloids (PA) are widely distributed in plants throughout the world, frequently in species relevant for human consumption. Apart from the toxicity that these molecules can cause in humans and livestock, PA are also known for their wide ...
Rute Moreira+3 more
semanticscholar +1 more source
In recent times, machine learning has become increasingly prominent in predictive toxicology as it has shifted from in vivo studies toward in silico studies.
Marcus W H Wang+2 more
semanticscholar +1 more source