Results 41 to 50 of about 383,704 (324)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
T-cell receptor Vβ8 for detection of biologically active streptococcal pyrogenic exotoxin type C
Journal of Dairy Science, 2023 : Streptococcus pyogenes is an important human pathogen, commonly spread by airborne droplets but also by ingestion of contaminated food. Apart from causing infection, this pathogen produces 13 distinct types of streptococcal pyrogenic exotoxins (SPE ...
Reuven Rasooly +2 more
doaj
Fluid flow enhances the effectiveness of toxin export by aquatic microorganisms: a first-passage perspective on microvilli and the concentration boundary layer [PDF]
, 2014 A central challenge for organisms during development is determining a means to efficiently export toxic molecules from inside the developing embryo. For aquatic microorganisms, the strategies employed should be robust with respect to the variable ocean environment and limit the chances that exported toxins are reabsorbed.
arxiv +1 more source
JAMA: The Journal of the American Medical Association, 1899 The human body, in its normal or its pathologic state is the theater of the toxic elaborations carried on either by the organism itself, or by the microbes which are normal inhabitants, or by those which are guests of the alimentary canal. In the first rank come the mineral substances taken with our food, even the most inoffensive, particularly on ...
openaire +2 more sources
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Aerosol and Air Quality ResearchThe concentration of 16 PAHs and 13 nitro-PAHs bound to total suspended particles were evaluated in outdoor environments in three cluster study locations in the western side of Taiwan. Samples were collected based on U.S. EPA, Method 23A, 1996 with XAD-2,
Hsin-Chieh Kung +3 more
doaj +1 more source
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Biocontrol of Escherichia coli O157:H7 by Enterobacter asburiae AEB30 on intact cantaloupe melons
Microbial BiotechnologyEscherichia coli O157:H7 causes >73,000 foodborne illnesses in the United States annually, many of which have been associated with fresh ready‐to‐eat produce including cantaloupe melons.
Thao D. Tran +3 more
doaj +1 more source
A Monoclonal–Monoclonal Antibody Based Capture ELISA for Abrin
Toxins, 2017 Abrin, one of the most highly potent toxins in the world, is derived from the plant, Abrus precatorius. Because of its high toxicity, it poses potential bioterror risks.
Christina C. Tam +5 more
doaj +1 more source