Results 81 to 90 of about 761,190 (342)
Phytochemistry, 2006 HC-toxin is a cyclic tetrapeptide of structure cyclo(D-Pro-L-Ala-D-Ala-L-Aeo), where Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid. It is a determinant of specificity and virulence in the interaction between the producing fungus, Cochliobolus carbonum, and its host, maize.
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Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Development and Characterization of Monoclonal Antibodies to Botulinum Neurotoxin Type E
Toxins, 2019 Botulism is a devastating disease caused by botulinum neurotoxins (BoNTs) secreted primarily by Clostridium botulinum. Mouse bioassays without co-inoculation with antibodies are the standard method for the detection of BoNTs, but are not capable of ...
Candace S. Bever +4 more
doaj +1 more source
Qualitative comparison of cassiicolin in four strains of Corynespora cassiicola [PDF]
, 2008 Corynespora cassiicola is a necrotrophic ascomycete fungus affecting a wide range of plants. In rubber tree, C. cassiicola causes the Corynespora Leaf Fall (CLF) disease, responsible for sporadic but often severe epidemics in rubber plantations in most ...
Bieysse, Daniel +4 more
core
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Role of Cytolethal Distending Toxin in Altered Stool Form and Bowel Phenotypes in a Rat Model of Post-infectious Irritable Bowel Syndrome. [PDF]
, 2012 Background/aimsCampylobacter jejuni infection is a leading cause of acute gastroenteritis, which is a trigger for post-infectious irritable bowel syndrome (PI-IBS). Cytolethal distending toxin (CDT) is expressed by enteric pathogens that cause PI-IBS. We
Alpern, Joel +12 more
core +1 more source
On the Toxin of Eclampsia [PDF]
The Boston Medical and Surgical Journal, 1908 n ...
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, 2023 The most often used medication in hospitals is oxygen, which is a crucial component in prehospital treatment. Prehospital providers administer oxygen to eliminate hypoxemia and hypoxia. Clinical settings of oxygen toxicity are categorized into acute oxygen toxin and habitual (chronic) oxygen toxin.
Pavan Eshwar Reddy.K +7 more
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Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source