FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Alternaria alternata leaf spot pathogens : genetics, evolutionary history and diagnostics [PDF]
The primary objective of this study was to characterise the Alternaria alternata species group. Particular focus was put on understanding the pathogens Alternaria mali and Alternaria gaisen, responsible for leaf spot diseases of apple and pear and of ...
Armitage, Andrew D.
core
How ricin and shiga toxin reach the cytosol of target cells : retrotranslocation from the endoplasmic reticulum [PDF]
, 2012 A number of protein toxins bind at the surface of mammalian cells and after endocytosis traffic to the endoplasmic reticulum, where the toxic A chains are liberated from the holotoxin.
Lord, Mike, Spooner, Robert A.
core
Complete Genome Sequence of Corynebacterium ulcerans Strain TSU-28, Harboring Two Diphtheria Toxin Genes, Isolated from a Patient with Diphtheria-Like Symptoms. [PDF]
Microbiol Resour Announc, 2023 Kawase J +6 more
europepmc +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Prevalence, antimicrobial resistance, and staphylococcal toxin genes of bla<sub>TEM-1a</sub> -producing Staphylococcus aureus isolated from animals in Chongqing, China. [PDF]
Vet Med Sci, 2023 Dong Q +5 more
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control [PDF]
, 2015 The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
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Frontiers in Cellular and Infection MicrobiologyBackgroundClostridioides difficile is a significant cause of healthcare-associated infections, with rising antimicrobial resistance complicating treatment. This study offers a genomic analysis of C.
Mohammad Sholeh +7 more
doaj +1 more source
Expression of full and fragment-B of diphtheria toxin genes in Escherichia coli for generating of recombinant diphtheria vaccines. [PDF]
Clin Exp Vaccine Res, 2022 Abulmagd S, Khattab AEA, Zedan H.
europepmc +1 more source