Results 111 to 120 of about 919,409 (398)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

A Multiomics Approach Unravels New Toxins With Possible In Silico Antimicrobial, Antiviral, and Antitumoral Activities in the Venom of Acanthoscurria rondoniae

Frontiers in Pharmacology, 2020
The Araneae order is considered one of the most successful groups among venomous animals in the world. An important factor for this success is the production of venoms, a refined biological fluid rich in proteins, short peptides and cysteine-rich ...
Guilherme A. Câmara, Milton Y. Nishiyama-Jr, Eduardo S. Kitano, Ursula C. Oliveira, Pedro I. da Silva, Inácio L. Junqueira-de-Azevedo, Alexandre K. Tashima, Alexandre K. Tashima   +7 more
doaj   +1 more source

Fish Advisories: Useful Or Difficult to Interpret? [PDF]

, 1996
The authors note that fish and shellfish offer significant exposure to environmental toxins but find that consumer knowledge and other factors may limit efforts to control risk in urban ...
Burger, Joanna, Gochfeld, Michael
core   +1 more source

The Development of Toad Toxins as Potential Therapeutic Agents

Toxins, 2018
Toxins from toads have long been known to contain rich chemicals with great pharmaceutical potential. Recent studies have shown more than 100 such chemical components, including peptides, steroids, indole alkaloids, bufogargarizanines, organic acids, and
Ji Qi, Abu Hasanat Md Zulfiker, Chun Li, David Good, M. Wei   +4 more
semanticscholar   +1 more source

Hyaluronan breakdown by snake venom hyaluronidases: From toxins delivery to immunopathology [PDF]

, 2023
Felipe Silva de França, Denise V. Tambourgi   +1 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Rapid and Simultaneous Detection of Aflatoxin B1, Zearalenone, and T-2 Toxin in Medicinal and Edible Food Using Gold Immunochromatographic Test Strip [PDF]

, 2023
Jiaying Zhang, Xiujiang Li, Jianhua Xie, Zhibing Huang   +3 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Development and validation of a LC-MS method for the quantification of microcystins in fish for their monitoring in environmental and food context

Journal of Agriculture and Food Research
Cyanobacterial blooms in aquatic ecosystems can result in the accumulation of cyanotoxins in other organisms. Fish can potentially accumulate large amounts of cyanotoxins through their direct interaction with contaminated water and the ingestion of ...
Camille Van Camp, Wannes Hugo R. Van Hassel, Jeroen Van Wichelen, Julien Masquelier   +3 more
doaj   +1 more source

Accumulation of Dinophysis Toxins in Bivalve Molluscs

Toxins, 2018
Several species of the dinoflagellate genus Dinophysis produce toxins that accumulate in bivalves when they feed on populations of these organisms. The accumulated toxins can lead to intoxication in consumers of the affected bivalves.
J. Blanco
semanticscholar   +1 more source