Results 91 to 100 of about 323,812 (313)

Development and validation of a LC-MS method for the quantification of microcystins in fish for their monitoring in environmental and food context

open access: yesJournal of Agriculture and Food Research
Cyanobacterial blooms in aquatic ecosystems can result in the accumulation of cyanotoxins in other organisms. Fish can potentially accumulate large amounts of cyanotoxins through their direct interaction with contaminated water and the ingestion of ...
Camille Van Camp   +3 more
doaj   +1 more source

Antifungal Activity against Filamentous Fungi of Ts1, a Multifunctional Toxin from Tityus serrulatus Scorpion Venom

open access: yesFrontiers in Microbiology, 2017
Antimicrobial peptides (AMPs) are ubiquitous and multipotent components of the innate immune defense arsenal used by both prokaryotic and eukaryotic organisms.
Welligton M. Santussi   +5 more
doaj   +1 more source

Marine Toxins Detection by Biosensors Based on Aptamers

open access: yes, 2019
Marine toxins cause great harm to human health through seafood, therefore, it is urgent to exploit new marine toxins detection methods with the merits of high sensitivity and specificity, low detection limit, convenience, and high efficiency. Aptasensors
Zhaoming Liu   +6 more
core   +1 more source

The Buzz about ADP-Ribosylation Toxins from Paenibacillus larvae, the Causative Agent of American Foulbrood in Honey Bees

open access: yes, 2021
The Gram-positive, spore-forming bacterium Paenibacillus larvae is the etiological agent of American Foulbrood, a highly contagious and often fatal honey bee brood disease. The species P.
Elke Genersch   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Consequences of Androctonus mauretanicus and Buthus occitanus scorpion venoms on electrolyte levels in rabbits

open access: yesHeliyon, 2017
Androctonus mauretanicus (A. mauretanicus) and Buthus occitanus (B. occitanus) scorpions, which belong to the Buthidae family, are the most venomous scorpions in Morocco.
Khadija Daoudi   +7 more
doaj   +1 more source

RTX Toxins of Animal Pathogens and Their Role as Antigens in Vaccines and Diagnostics

open access: yes, 2019
Exotoxins play a central role in the pathologies caused by most major bacterial animal pathogens. The large variety of vertebrate and invertebrate hosts in the animal kingdom is reflected by a large variety of bacterial pathogens and toxins. The group of
Joachim Frey
core   +1 more source

Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins

open access: yes, 2020
Mono-ADP-ribosyltransferase toxins are often key virulence factors produced by pathogenic bacteria as tools to compromise the target host cell. These toxins are enzymes that use host cellular NAD+ as the substrate to modify a critical macromolecule ...
Miguel R. Lugo, Allan R. Merrill
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Miscellaneous Marine Toxins of Medical Significance

open access: yes, 2016
Subaquatic life is in a state of constant mechanical and chemical warfare in which the best adapted will survive. In these complex interactions, some animals can present structures that will inflict trauma, such as teeth, spines, and stings, which can be
Gopalakrishnakone, P.   +5 more
core   +1 more source

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