Results 111 to 120 of about 323,812 (313)

Preliminary Investigation of GC–MS Profiling and Antibacterial Activities of Different Solvent Extracts From Litchi chinensis Sonn. Seed

Scientifica
Traditionally different parts of Litchi chinensis Sonn. (Family: Sapindaceae) have been used medicinally to treat a variety of diseases, including stomach ulcers, flatulence, obesity, cough, diabetes, and hernia-like situations.
Samia Sharmin, Ali Ahsan Muzahid, Md. Mohibul Islam, Mst. Sarmina Yeasmin, Amit Kumar Dey, Md. Jasim Uddin, G. M. Masud Rana, Jaytirmoy Barmon, Safaet Alam, Md. Nurul Huda Bhuiyan, Nazim Uddin Ahmed   +10 more
doaj   +1 more source

Clinical and immunological comparison of COVID-19 disease between critical and non-critical courses: a systematic review and meta-analysis

Frontiers in Immunology
IntroductionAcute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which appeared in 2019, has been classified as critical and non-critical according to clinical signs and symptoms. Critical patients require mechanical ventilation and intensive care unit
Mojtaba Hedayati-Ch, Mojtaba Hedayati-Ch, Hadi Sedigh Ebrahim-Saraie, Arash Bakhshi   +3 more
doaj   +1 more source

Dynamics of the cyanobacterial water bloom with focus to Microcystis and its relationship with environmental factors in Brno reservoir

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
Our paper brings new information about long-term changes of the phytoplankton communities in the Brno reservoir with the focus on the Microcystis abundance using the semi-monthly monitoring data covering the period 2006–2012.
Lucie Straková, Radovan Kopp, Eliška Maršálková, Blahoslav Maršálek   +3 more
doaj   +1 more source

Uremic Toxins and Atrial Fibrillation: Mechanisms and Therapeutic Implications

, 2019
Atrial fibrillation (AF) is the most prevalent arrhythmia in the general population. There is a close association between chronic kidney disease (CKD) and AF.
Masaki Ieda, Fumi Yamagami, Kazuko Tajiri, Dai Yumino   +3 more
core   +1 more source

Targeting Uremic Toxins to Prevent Peripheral Vascular Complications in Chronic Kidney Disease

, 2020
Chronic kidney disease (CKD) exhibits progressive kidney dysfunction and leads to disturbed homeostasis, including accumulation of uremic toxins, activated renin-angiotensin system, and increased oxidative stress and proinflammatory cytokines.
Der-Cherng Tarng, Chia-Lin Wu
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Validation of an LC-MS Method for Quantification of Mycotoxins and Characterization of Fungal Strains Occurring in Food and Feed

Chemosensors
Mycotoxins are naturally occurring secondary metabolites produced by specific fungal strains. They can cause adverse effects, posing a serious health threat to both humans and livestock.
Julien Masquelier, Emmanuel K. Tangni, Pierre Becker, Julie Sanders, Joëlle Laporte, Birgit Mertens   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Bacterial Protein Toxins as Anticancer Agents: Clinical Potential of Pseudomonas and Anthrax Toxins

Protein toxins are biologically active polypeptides produced by a variety of organisms, including bacteria, plants, fungi, and animals. These molecules exert potent and specific toxic effects on target cells and are primarily associated with ...
Radhika Gupta, Vishal Sharma, Namita Nayyar, Yogendra Singh, Renu Baweja, Richa Misra, Ritvik Baweja   +6 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source