Results 41 to 50 of about 100,749 (257)

Cholera toxin

Bioscience Reports, 1977
Summary1. Death in several infectious diseases is caused by protein toxins secreted by invading bacteria. Cholera toxin is a simple protein secreted by Vibrio cholerae colonizing the gut; it is responsible for the massive diarrhoea that is cholera.2. The primary action of cholera toxin is an activation of adenylate cyclase, an enzyme found on the inner
openaire   +3 more sources

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Hemorrhagic Activity and Hemostatic Alterations Caused by Cerastes cerastes and Daboia mauritanica: Indicators of Viper Bite Severity in Morocco [PDF]

BIO Web of Conferences
Snakebite envenoming is a major global public health problem, causing approximately 5 million bites and 150,000 deaths each year, particularly in North Africa, where viper bites lead to significant morbidity and mortality.
Mesmoudi Nihal, Hammani Noureddine, Ammouch Khawla, Ibenmoussa Samir, Moustaghfir Abdellah, Oukkache Naoual   +5 more
doaj   +1 more source

Membrane‐Damaging Toxins: Family of RTX Toxins

, 2003
The major cellular effect of RTX toxins has been ascribed to their pore‐forming capacity, resulting in plasma membrane lesions and osmotic lysis.
Oxhamre, C, Richter‐Dahlfors, A
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Proteomic Profiling of Extracellular Vesicles Isolated from Plasma and Peritoneal Exudate in Mice Induced by Crotalus scutulatus scutulatus Crude Venom and Its Purified Cysteine-Rich Secretory Protein (Css-CRiSP)

Toxins, 2023
Increased vascular permeability is a frequent outcome of viperid snakebite envenomation, leading to local and systemic complications. We reported that snake venom cysteine-rich secretory proteins (svCRiSPs) from North American pit vipers increase ...
Armando Reyes, Joseph D. Hatcher, Emelyn Salazar, Jacob Galan, Anton Iliuk, Elda E. Sanchez, Montamas Suntravat   +6 more
doaj   +1 more source

Food-Derived Uremic Toxins in Chronic Kidney Disease

, 2023
Patients with chronic kidney disease (CKD) have a higher cardiovascular risk compared to the average population, and this is partially due to the plasma accumulation of solutes known as uremic toxins.
Meijers, Bjorn, Ricard Farré, Saskia Adriana Overbeek, Farre, Ricard, Björn Meijers, Mara Lauriola, Pieter Evenepoel, Lauriola, Mara, Evenepoel, Pieter, Overbeek, Saskia Adriana   +9 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

RASGRP4 is a key factor in the KRAS activation mediated by SOS in tumor Y1 adrenocortical cell lines

Scientific Reports
The Y1 mouse adrenocortical carcinoma cell line presents amplification of the KRas oncogene and high-basal levels of KRAS-GTP mediated by the GEF SOS. In this research, we developed a dynamic model based on ordinary differential equations of the KRAS-GTP
Fabio Montoni, Rosangela Aparecida Moreira Wailemann, Thompson Eusébio Pavan Torres, Katia Andrea Menezes de Torres, Cecilia Sella Fonseca, Marcelo da Silva Reis, Hugo Aguirre Armelin   +6 more
doaj   +1 more source

The Toxins of Cyanobacteria [PDF]

Acta Medica (Hradec Kralove, Czech Republic), 2001
Cyanobacteria , formerly called ”blue-green algae“, are simple, primitive photosynthetic microorganism wide occurrence in fresh, brackish and salt waters. Forty different genera of Cyanobacteria are known and many of them are producers of potent toxins responsible for a ...
openaire   +3 more sources