Results 61 to 70 of about 357,640 (306)

Snake venom cysteine-rich secretory protein from Mojave rattlesnake venom (Css-CRiSP) induces acute inflammatory responses on different experimental models

open access: yesToxicon: X
Snake venoms contain various molecules known for activating innate immunity and causing local effects associated with increased vascular permeability, such as vascular leakage and edema, common symptoms seen in snakebite envenomings. We have demonstrated
Emelyn Salazar   +6 more
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak   +9 more
wiley   +1 more source

IN VITRO ANTIBACTERIAL ACTIVITY OF SOME PLANT ESSENTIAL OILS [PDF]

open access: yesJournal of Food and Dairy Sciences, 2008
In this study we aim to in vitro evaluate the antibacterial activity of 15 plant essential oils against six bacterial species. Antibacterial effects of the selected essential oils were investigated against four gram-negative bacteria (Escherichia coli ...
Y. Abo-Srea   +3 more
doaj   +1 more source

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques   +5 more
wiley   +1 more source

Antibodies and Vaccines Against Botulinum Toxins: Available Measures and Novel Approaches

open access: yes, 2019
International audienceBotulinum neurotoxin (BoNT) is produced by the anaerobic, Gram-positive bacterium Clostridium botulinum. As one of the most poisonous toxins known and a potential bioterrosism agent, BoNT is characterized by a complex mode of action
Rasetti-Escargueil, Christine   +3 more
core   +1 more source

The Cytocidal Spectrum of Bacillus thuringiensis Toxins: From Insects to Human Cancer Cells

open access: yes, 2020
Bacillus thuringiensis (Bt) is a ubiquitous bacterium in soils, insect cadavers, phylloplane, water, and stored grain, that produces several proteins, each one toxic to different biological targets such as insects, nematodes, mites, protozoa, and ...
Gretel Mendoza-Almanza   +6 more
core   +1 more source

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim   +11 more
wiley   +1 more source

ATP-Binding Cassette Subfamily a Member 2 Is a Functional Receptor for Bacillus thuringiensis Cry2A Toxins in Bombyx mori, But Not for Cry1A, Cry1C, Cry1D, Cry1F, or Cry9A Toxins

open access: yes, 2020
Cry toxins are insecticidal proteins produced by Bacillus thuringiensis (Bt). They are used commercially to control insect pests since they are very active in specific insects and are harmless to the environment and human health.
Satomi Adegawa   +7 more
core   +1 more source

Are toxins from harmful algae a factor involved in the decline of harbour seal populations in Scotland? [PDF]

open access: yes, 2015
Firstly this study builds on the investigation initiated by Hall and Frame (2010), which found that Scottish harbour seals were exposed to domoic acid (DA), a potent natural neurotoxin produced by phytoplankton.
Jensen, Silje-Kristin
core   +1 more source

From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery

open access: yesFrontiers in Pharmacology, 2020
Animal poisons and venoms are comprised of different classes of molecules displaying wide-ranging pharmacological activities. This review aims to provide an in-depth view of toxin-based compounds from terrestrial and marine organisms used as diagnostic ...
Karla de Castro Figueiredo Bordon   +15 more
doaj   +1 more source

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