Results 91 to 100 of about 62,117 (268)

Maternal Tetanus Toxoid Vaccination and Neonatal Mortality in Rural North India

open access: yesPLoS ONE, 2012
Objectives Preventable neonatal mortality due to tetanus infection remains common. We aimed to examine antenatal vaccination impact in a context of continuing high neonatal mortality in rural northern India.
Abhishek Singh   +3 more
semanticscholar   +1 more source

Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development

open access: yesTropical Medicine &International Health, Volume 31, Issue 3, Page 295-306, March 2026.
ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Vaidehi Nafade   +4 more
wiley   +1 more source

A humanized NOG‐EXL mouse model for producing severe fever with thrombocytopenia syndrome virus–reactive human antibodies

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 2, Page 378-388, February 2026.
Humanized mouse models are essential for studying human immune response and antibody development. However, conventional models exhibit limited B cell maturation and antigen‐specific humoral responses. To overcome these limitations, we used the NOG‐EXL mice expressing human interleukin 3 (IL‐3) and granulocyte‐macrophage colony‐stimulating factor (GM ...
Dong Hoon Lee   +11 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

The development of contraceptive vaccines [PDF]

open access: yes, 2002
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning.
Delves, PJ
core   +1 more source

Modern approaches to vaccines interchangeability

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
Research findings demonstrate the possibility of replacing the vaccines, when used in accordance with the recommended dosage and administration schedule specified by the manufacturer.
I. I. Snegireva   +4 more
doaj  

Vaccine coverage and determinants of incomplete vaccination in children aged 12-23 months in dschang, west region, cameroon: a cross-sectional survey during a polio outbreak [PDF]

open access: yes, 2015
Inadequate immunization coverage with increased risk of vaccine preventable diseases outbreaksremains a problem in Africa. Moreover, different factors contribute to incomplete vaccination status. This study wasperformed in Dschang (West Region, Cameroon),
Biguioh, Rodrigue Mabvouna   +8 more
core   +2 more sources

Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues

open access: yesJournal of Experimental Medicine, 1993
Antigen-specific B cell responses to mucosally delivered proteins are dependent upon CD4-positive T helper (Th) cells, and the frequency of Th1 and Th2 cell responses after oral immunization may determine the level and isotype of mucosal antibody ...
J. Xu-Amano   +8 more
semanticscholar   +1 more source

Do Childhood Vaccines Have Non-Specific Effects on Mortality [PDF]

open access: yes, 2003
A recent article by Kristensen et al. suggested that measles vaccine and bacille Calmette–Guérin (BCG) vaccine might\ud reduce mortality beyond what is expected simply from protection against measles and tuberculosis.
Boyce , G. Thomas   +3 more
core  

Menstrual disorders in rural Gambia.

open access: yes, 2003
As part of a community-based reproductive morbidity survey in rural Gambia, the prevalence and association of menstrual disorders with sociodemographic characteristics and other reproductive morbidities, and with knowledge, attitudes, and beliefs ...
Coleman, Rosalind   +5 more
core   +1 more source

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