Results 11 to 20 of about 41,564 (262)

Toxicity and immunogenicity of Enterotoxigenic Escherichia coli heat-labile and heat-stable toxoid fusion 3xSTa(A14Q)-LT(S63K/R192G/L211A) in a murine model. [PDF]

PLoS ONE, 2013
Diarrhea is the second leading cause of death to young children. Enterotoxigenic Escherichia coli (ETEC) are the most common bacteria causing diarrhea. Adhesins and enterotoxins are the virulence determinants in ETEC diarrhea.
Chengxian Zhang, David E Knudsen, Mei Liu, Donald C Robertson, Weiping Zhang, STa Toxoid Vaccine Consortium Group   +5 more
doaj   +2 more sources

Reactogenicity and immunogenicity of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant and nonpregnant women

Vaccine, 2018
Kimberly B. Fortner, Geeta K. Swamy, Karen R. Broder, Natalia Jimenez‐Truque, Yuwei Zhu, Pedro L. Moro, Jennifer L. Liang, Emmanuel B. Walter, R. Phillips Heine, M. Anthony Moody, Sandra Yoder, Kathryn M. Edwards   +11 more
openalex   +3 more sources

The role of timely initiation of antenatal care on protective dose tetanus toxoid immunization: the case of northern Ethiopia post natal mothers [PDF]

BMC Pregnancy and Childbirth, 2018
BackgroundGlobally, tetanus toxoid protective dose immunization of the mothers is one of the strategies of maternal and neonatal tetanus prevention. Ethiopia has planned the national tetanus protection at birth coverage to reach 86% by the year 2015 ...
Muhabaw Shumye Mihret, Miteku Andualem Limenih, Temesgen Worku Gudayu   +2 more
openalex   +2 more sources

Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice

Science Translational Medicine, 2022
Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic disease. Tumors are poorly immunogenic and immunosuppressive, preventing T cell activation in the tumor microenvironment.
B. Selvanesan, D. Chandra, Wilber Quispe-Tintaya, Arthee Jahangir, Ankur Patel, K. Meena, Rodrigo Alberto Alves Da Silva, Madeline Friedman, L. Gabor, Olivia Khouri, S. Libutti, Ziqiang Yuan, Jenny Li, Sarah Siddiqui, A. Beck, L. Tesfa, W. Koba, J. Chuy, J. Mcauliffe, Rojin Jafari, D. Entenberg, Yarong Wang, J. Condeelis, Vera M. Desmarais, V. Balachandran, Xusheng Zhang, Ken Lin, C. Gravekamp   +27 more
semanticscholar   +1 more source

SARS-CoV-2 RBD-Tetanus toxoid conjugate vaccine induces a strong neutralizing immunity in preclinical studies

bioRxiv, 2021
Controlling the global COVID-19 pandemic depends, among other measures, on developing preventive vaccines at an unprecedented pace. Vaccines approved for use and those in development intend to use neutralizing antibodies to block viral sites binding to ...
Yury Valdés-Balbín, Darielys Santana-Mederos, Lauren Quintero, S. Fernandez, Laura Rodriguez, B. S. Ramírez, Rocmira Perez, Claudia Acosta, Y. Méndez, M. G. Ricardo, Tays Hernández, Gretchen Bergado, Franciscary Pi, A. Valdes, T. Carmenate, Ubel Ramírez, R. Oliva, J. Soubal, Raine Garrido, Félix Cardoso, M. Landys, H. González, M. Fariñas, J. Enriquez, E. Noa, A. Suarez, Cheng Fang, L. A. Espinosa, Y. Ramos, L. González, Yanet Climent, G. Rojas, Ernesto Relova-Hernández, Y. Infante, Sum Lai Losada, T. Boggiano, E. Ojito, K. L. Monzón, F. Chiodo, F. Paquet, Guang-Wu Chen, Daniel G. Rivera, D. García-Rivera, V. Verez-Bencomo   +43 more
semanticscholar   +1 more source

Tetanus Toxoid Vaccination Coverage and Associated Factors among Childbearing Women in Ethiopia: A Systematic Review and Meta-Analysis

BioMed Research International, 2021
Background Tetanus is a bacterial disease caused by the Clostridium tetani, which is a highly fatal, noncommunicable, and toxin-mediated disease. Globally, maternal and neonatal tetanus is a public health problem due to low maternal tetanus toxoid ...
Jemberu Nigussie, Bekahegn Girma, A. Molla, Moges Mareg   +3 more
semanticscholar   +1 more source

Individual and community-level determinants of poor tetanus toxoid immunization among pregnant women in Ethiopia using data from 2016 Ethiopian demographic and health survey; multilevel analysis

Archives of Public Health, 2021
Background Tetanus is a vaccine-preventable disease that can occur in all populations, with neonates and pregnant women being at the most risk. Ethiopia has the highest maternal and neonatal tetanus morbidity and mortality rates.
Alemneh Mekuriaw Liyew, Hiwot Ayalew
semanticscholar   +1 more source

Tetanus, Diphtheria, and Acellular Pertussis Vaccination Coverage Among Publicly Insured Pregnant Women, U.S., 2016–2019

AJPM Focus, 2023
Introduction: Vaccination with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine during pregnancy is highly effective against Bordetella pertussis in young infants.
Cheryl J. Isenhour, DVM, Tami H. Skoff, MS, Megan C. Lindley, MPH, Fangjun Zhou, PhD, Susan Hariri, PhD   +4 more
doaj   +1 more source

BIOLOGICAL PROPERTIES AND MEDICAL APPLICATION OF DIPHTHERIA TOXIN DERIVATIVES [PDF]

Biotechnologia Acta, 2018
The aim of the review was to analyze the literature data related to the application of a variety of diphtheria toxin derivatives. Although studies of the diphtheria toxin interaction with sensitive and resistant mammalian cells have been held for a ...
Manoilov K.Y.
doaj   +1 more source

Investigation of the Effect of PEG Detoxification on Diphtheria Vaccine [PDF]

Archives of Razi Institute, 2022
Immunization has been considered a successful global health program that saves many persons’ lives each year. The vaccines reduce the risk of getting the disease by building immunity in the body. Therefore, the constant availability of essential vaccines
T Hesari, F Tahoori, A Nazari, Z Salehi Najafabadi, M Samianifard, A Faramarzi, M Soleimani   +6 more
doaj   +1 more source