Results 31 to 40 of about 41,564 (262)
DEVELOPMENT OF THE VACCINE BASED ON THE RECOMBINANT ANTIGENS OF PSEUDOMONAS AERUGINOSA
Журнал микробиологии, эпидемиологии и иммунобиологии, 2019 Aim. The aim is obtaining, investigation and selection of recombinant antigens for inclusion theirs into the against Pseudomonas vaccine. Materials and methods. The genes encoding of the outer membrane proteins F, L and I and Exotoxin A were synthesized
N. A. Mihailova +3 more
doaj +1 more source
Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB)
Toxins, 2019 Staphylococcus aureus (SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, S. aureus thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins.
Shweta Kailasan +11 more
semanticscholar +1 more source
NECESSITY OF TRANSLOCATION DOMAIN FOR REALISATION OF CYTOSTATIC EFFECT OF NON-TOXIC DERIVATIVES OF DIPHTHERIA TOXIN [PDF]
Biotechnologia Acta, 2018 The aim of the work was to evaluate in vitro the cytostatic effect of recombinant fragments of the non-toxic point mutant of diphtheria toxin — CRM197, which was suggested as a potent medication for treatment of triple negative breast cancer.
K. Y. Manoilov +4 more
doaj +1 more source
Frontiers in Microbiology, 2018 Enterotoxigenic Escherichia coli (ETEC) bacteria remain a leading cause of children's diarrhea and travelers' diarrhea. Vaccines that induce antibodies to block ETEC bacterial adherence and to neutralize toxin enterotoxicity can be effective against ETEC-
Qiangde Duan +6 more
semanticscholar +1 more source
PRECLINICAL STUDIES OF RECOMBINANT PSEUDOMONAS VACCINE
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Aim. Evaluation of the efficacy and safety of the three experimental lots of Recombinant Pseudomonas Vaccine. Materials and methods. The preparation contained the recombinant proteins OprF and toxoid that were purified by chromatography in nickel ...
N. A. Mihailova +4 more
doaj +1 more source
Maternal Tetanus Toxoid Vaccination in Benin: Evidence from the Demographic and Health Survey
Vaccines, 2022 Tetanus toxoid vaccination is critical for improving maternal and child health. Yet, the prevalence and correlates of maternal tetanus toxoid vaccination coverage remain largely underexplored in Benin where infant and child mortality rates are high ...
Daniel Amoak +4 more
doaj +1 more source
Tetanus toxoid and CCL3 improve DC vaccines in mice and glioblastoma patients
Nature, 2015 After stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce immune responses. As such, autologous DCs generated ex vivo have been pulsed with tumour antigens and injected back into patients as immunotherapy.
D. Mitchell +18 more
semanticscholar +1 more source
METHODS OF CONTROL DIPHTHERIA VACCINE SAFETY [PDF]
Annals of Mechnikov's Institute, 2016 Vaccination success depends not only on the timely coverage of threatened contingents, but also on the quality of vaccines. Every day, the requirements for security guarantees vaccines and their use guarantees of security increases.
Isayenko Ye. Yu +5 more
doaj +1 more source
Journal of Arthropod-Borne Diseases, 2022 Background: Hemiscorpius lepturus is one of the most dangerous scorpions in Iran and the world. Numerous studies have been conducted on phospholipases, especially phospholipase D, in this scorpion’s venom, and the results have shown this protein to be ...
Narges Safari-Foroushani +4 more
doaj +1 more source
Development of an enterotoxigenic Escherichia coli vaccine based on the heat-stable toxin
Human Vaccines & Immunotherapeutics, 2019 Infection with enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea-related illness and death among children under 5 years of age in low– and middle-income countries (LMIC). Recent studies have found that it is the ETEC subtypes that
Ephrem Debebe Zegeye +3 more
doaj +1 more source