Results 61 to 70 of about 41,564 (262)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Seroprevalence of diphtheria toxoid IgG antibodies in children, adolescents and adults in Poland

open access: yesBMC Infectious Diseases, 2013
BackgroundRecommendations for diphtheria immunization are to apply an effective primary immunization in infancy and to maintain immunity throughout life. Immunity against diphtheria depends primarily on antibody to the diphtheria toxin.
A. Zasada   +3 more
semanticscholar   +1 more source

A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile

open access: yesMicrobiology, 2013
The Clostridium difficile toxins A and B are primarily responsible for symptoms of C. difficile associated disease and are prime targets for vaccine development.
R. Donald   +16 more
semanticscholar   +1 more source

Combination Vaccination With Tetanus Toxoid and Enhanced Tumor-Cell Based Vaccine Against Cervical Cancer in a Mouse Model

open access: yesFrontiers in Immunology, 2020
Cervical cancer is the fourth most common cancer in women with an estimated 570,000 new cases in 2018 which constitute about 6. 6% of all cancers in women according to WHO report 2018.
Donia Alson   +7 more
doaj   +1 more source

Spatial distribution and determinants of tetanus toxoid immunization among pregnant women in Ethiopia using data from Ethiopian demographic and health survey 2016

open access: yesBMC Pregnancy and Childbirth, 2023
Introduction Tetanus is a major public health problem caused by clostridium tetani. Although it is vaccine-preventable, the case fatality rate among neonates in areas with poor immunization coverage and limited access to clean deliveries reaches 80-100%.
Beletech Fentie   +19 more
doaj   +1 more source

Perspectives on Pertussis Prevention

open access: yes
Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

mRNA Cancer Vaccines: From Pandemic Paradigm to Personalized Oncology Therapeutics

open access: yesCancer Innovation, Volume 4, Issue 6, December 2025.
This review highlights the transformative potential of mRNA cancer vaccines, leveraging technological advancements in nucleotide modification, lipid nanoparticle delivery, and AI‐driven neoantigen selection to enhance vaccine stability, immunogenicity, and personalization.
Bo Yang, Juan Liu, Yang Li, Xiaoxuan Liu
wiley   +1 more source

Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards [PDF]

open access: yesOsong Public Health and Research Perspectives, 2018
Objectives Vaccinations against diphtheria and tetanus are essential in providing immunity against these bacterial infections. The potency of diphtheria and tetanus toxoid vaccines can be measured using the in vivo toxin neutralization assay.
Chan Woong Choi   +7 more
doaj   +1 more source

Lightning‐Induced Keraunoparalysis and Rhabdomyolysis: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Lightning‐induced keraunoparalysis is a transient, reversible paralysis that can mimic spinal cord injury, while rhabdomyolysis—even without renal impairment—may coexist. Early recognition, vigilant monitoring, and correction of electrolyte disturbances such as hypokalemia are crucial.
Sushmita Bhattarai   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy