Results 61 to 70 of about 27,758 (226)

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source

A biomimetic nanoparticle-enabled toxoid vaccine against melittin [PDF]

, 2018
 Tianyi Kang,1 Chenyang Li,1,2 Ting Du,1 Yujiao Wu,1 Yuping Yang,1 Xuan Liu,1 Qianqian Zhang,1 Xiaoping Xu,3 Maling Gou1,4 1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, People&rsquo ...
Liu X, Yang Y, Li C, Du T, Kang T, Gou M, Xu X, Wu Y, Zhang Q   +8 more
core  

Synthetic O‐Polysaccharide Backbone Units for a Single Antigen Vaccine Against Two Major Non‐Typhoidal Salmonella Serovars

Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.
A modular strategy was developed to synthesize tri‐, hexa‐, and nona‐saccharides representing repeating units of the conserved O‐polysaccharide backbone of Salmonella. Conjugates of these glycans to bacteriophage Qβ induced strong IgG responses in mice and rabbits. Antibodies elicited recognized native O‐polysaccharides and conferred protection against
Xingling Pan, Changxin Huo, Soham Maity, Herbert Kavunja, Rachel Moszyk, Cameron Talbot, Scott M. Baliban, Xuefei Huang   +7 more
wiley   +2 more sources

Tetanus-Toxoid Vaccination among Married Women of Reproductive Age (18-49) and its Association with Socio-demographic in Union Council Kamu Shaheed District Ghotki Sindh [PDF]

JLUMHS, 2019
OBJECTIVE: To determine the factors in influencing for tetanus toxoid vaccination among married women of reproductive age group (18-49) of Ghotki Sindh.
Abdul Wahab Somoro, Muhammad Ibrahim Ansari , Ghulam Parwar Soomro, Muhammad Aslam, Muhammad Siddique Ansari, Kaleemullah Abro   +5 more
doaj   +1 more source

Assay of Diphtheria Vaccine Potency by Intradermal Challenge Test

Эпидемиология и вакцинопрофилактика, 2023
Relevance. Modern identifying potency (immunogenicity) of diphtheria toxoid tests are based on determining immunized animals resistance for administration challenge toxin or evaluation of protective antibodies level in serum.
E. I. Komarovskaya, О. V. Perelygyna
doaj   +1 more source

Update on Selected Adverse Events of Concern Following Immunization With Acellular Pertussis Vaccines, a Narrative Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim To provide an update paper on evidence of adverse events of concern following immunization (AEFI) with pertussis vaccines, focusing primarily on acellular (aP) vaccines. Methods Evidence was synthesised from epidemiological studies, systematic reviews over recent decades, expert interpretations in reviews from relevant research teams and ...
Lennart Nilsson, Jann Storsaeter
wiley   +1 more source

Construction and detection of the 3xSTa_A14Q-tmLT toxoid fusion. [PDF]

, 2013
Panel A: Amino acid sequences of the native STa toxin and the STaA14Q toxoid. Panel B: Construction of the 3xSTaA14Q-tmLT toxoid fusion gene with 3 copies of the STaA14Q toxoid gene genetically fused at the 5’ end, within LTA, and the 3’ end of the ...
Mei Liu (41760), Donald C. Robertson (311522), Weiping Zhang (311523), Chengxian Zhang (469708), David E. Knudsen (469709)   +4 more
core   +1 more source

A Global Perspective of Childhood Vaccinations: Past, Present, and Future—From Smallpox to mRNA

Acta Paediatrica, EarlyView.
ABSTRACT Childhood immunisation is one of the most successful public health interventions in history, preventing millions of deaths and substantially reducing global child mortality. This mini‐review summarises the historical development of childhood vaccines, the role of global coordination in expanding immunisation coverage, and the innovations that ...
Tobias Alfvén, Tania Reza, Alieu Sowe
wiley   +1 more source

Subcutaneous immunisation with Tetanus toxoid. [PDF]

, 2012
Endpoint titres for IgG (A, C) and IgA (B, D) in sera (upper panels) and vaginal washes (lower panels) from animals immunised three times with Tetanus toxoid subcutaneously.
Robin J. Shattock (110684), Katja Klein (110677), Viviana Buffa (110672), Lucia Fischetti (110681)   +3 more
core   +1 more source

Patient‐Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next‐Generation Allergen Immunotherapy

Clinical &Experimental Allergy, EarlyView.
Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić, Marta Paolucci, Alessandro Streuli, David A. Melillo, Tianchi Jiang, Raffaela Campana, Claudia C. V. Lang, Thomas M. Kündig, Christian Steuer, Klaus Eyer, Pål Johansen   +10 more
wiley   +1 more source