Results 141 to 150 of about 144,290 (309)

Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses

Journal of Experimental Medicine, 2016
Gay et al. identify a Toxoplasma gondii secreted effector that recruits NuRD transcriptional repressor and blocks IFN-γ–stimulated STAT1-dependent gene expression, thus dampening host responses to infection.
Gabrielle Gay, L. Braun, M. Brenier-Pinchart, J. Vollaire, V. Josserand, R. Bertini, Aurélie Varesano, B. Touquet, Pieter-Jan De Bock, Y. Couté, I. Tardieux, Alexandre Bougdour, Mohamed-Ali Hakimi   +12 more
semanticscholar   +1 more source

Cell division in apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella [PDF]

, 2012
Apicomplexa are intracellular parasites that cause important human diseases including malaria and toxoplasmosis. During host cell infection new parasites are formed through a budding process that parcels out nuclei and organelles into multiple daughters.
de Leon, J.C., Demerly, J.L., Dubremetz, J.-F., Fellows, J.D., Francia, M.E., Jordan, C.N., Morrissette, N.S., Patel, J.D., Sheiner, L., Striepen, B.   +9 more
core   +1 more source

A novel approach for feline sporotrichosis pathogen detection based on loop‐mediated isothermal amplification

Veterinary Dermatology, EarlyView.
Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei, Júlia Campos, Amanda Bertão‐Santos, Alis Frentzel, Hugo Ávila, Fabiana S. Monti, Marconi R. Farias   +6 more
wiley   +1 more source

Host lipid droplets: An important source of lipids salvaged by the intracellular parasite Toxoplasma gondii

PLoS Pathogens, 2017
Toxoplasma is an obligate intracellular parasite that replicates in mammalian cells within a parasitophorous vacuole (PV) that does not fuse with any host organelles.
S. Nolan, J. Romano, I. Coppens
semanticscholar   +1 more source

Cytotoxic Signature and IFN‐γ Production Dominate CD4+ T‐Cell Response During Human Toxoplasmosis

Immunology, Volume 175, Issue 2, Page 151-164, June 2025.
Overview of CD4+ T‐cell subsets in patients with toxoplasmosis. Schematic drawing summarising the most important alterations in CD4+ T‐cell subsets, illustrated in different colours, from patients in distinct stages of toxoplasmosis, represented with different colours, with (lesion) or without (no lesion) ocular manifestations.
Priscilla Miranda Henriques, Gregório Guilherme Almeida, Inga Rimkute, Luara Isabela dos Santos, Thomas Liechti, Ana Paula Marino, Isabela Natália Pascoal Campos do Vale, Daniel Vitor Vasconcelos‐Santos, Olindo Assis Martins‐Filho, Ricardo Tostes Gazzinelli, Mario Roederer, Alan Sher, Andréa Teixeira‐Carvalho, Dragana Jankovic, Lis Ribeiro do Valle Antonelli   +14 more
wiley   +1 more source

Novel components of the Toxoplasma inner membrane complex revealed by BioID. [PDF]

, 2015
UNLABELLED:The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to a supporting cytoskeletal network. The IMC plays important roles in
Bell, Hannah N, Bentolila, Laurent A, Bradley, Peter J, Chen, Allan L, Huang, Amy S, Kim, Elliot W, Moon, Andy S, Rashoff, Andrew Q, Toh, Justin Y, Van, Christina, Vashisht, Ajay A, Wohlschlegel, James A   +11 more
core   +3 more sources

Stillbirth Caused by Vitamin A Deficiency in Captive African Lion Cubs (Panthera leo)

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Stillbirth caused by vitamin A deficiency in two African lion cubs. A 15‐year‐old captive lioness mated with a 12‐year‐old male lion and was fed about 4 kg of lean beef daily, without any supplements. Necropsy revealed diffuse congestion and haemorrhage in several organs.
Yashar Gharehaghajlou, Monireh Khordadmehr, Farinaz Jigari‐Asl, Mohammadreza Ghorani, Katayoon Nofouzi, Hassan Sadri   +5 more
wiley   +1 more source

A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii

Nature Communications, 2017
Apicomplexan parasites are typified by an apical complex that contains a unique microtubule-organizing center (MTOC) that organizes the cytoskeleton. In apicomplexan parasites such as Toxoplasma gondii, the apical complex includes a spiral cap of tubulin-
Shaojun Long, B. Anthony, Lisa L Drewry, L. Sibley   +3 more
semanticscholar   +1 more source

Toxoplasma gondii F-actin forms an extensive filamentous network required for material exchange and parasite maturation [PDF]

, 2017
Apicomplexan actin is important during the parasite's life cycle. Its polymerization kinetics are unusual, permitting only short, unstable F-actin filaments.
Abounit, Andenmatten, Angrisano, Angrisano, Baum, Belin, Bichet, Black, Burkel, Carlier, Dobrowolski, Dobrowolski, Dobrowolski, Donald, Drewry, Egarter, Foth, Francia, Haase, Harding, Heaslip, Hegge, Herm-Götz, Hliscs, Hu, Huynh, Håkansson, Jacot, Kühni-Boghenbor, Los, Loussert, Mehta, Meissner, Meissner, Mercier, Muñiz-Hernández, Olshina, Opitz, Pantaloni, Panza, Plessner, Riedl, Rocchetti, Salamun, Shaner, Shaw, Siden-Kiamos, Skillman, Skillman, Smulders, Steger, Sultana, Wetzel, Whitelaw   +53 more
core   +2 more sources

Pathological and Molecular Studies of Neospora caninum Infection in Aborted Bovine Foetuses in Khorasan Razavi Province, Iran

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
Aborted bovine foetuses were collected from dairy cattle in Khorasan Razavi province. Brain samples of aborted foetuses were tested to detect N.caninum infection using nested PCR and histopathological examination. In addition, blood samples were collected from dairy cattle that had aborted PCR‐positive foetuses and were analysed using ELISA .
Asma Keyvanlou Shahrestanaki, Hossein Nourani, Gholamreza Razmi   +2 more
wiley   +1 more source