Results 181 to 190 of about 141,956 (266)

<i>TP53</i>-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition. [PDF]

Sci Adv
Spinella JF, Chagraoui J, Moison C, Boivin I, Carpentier GR, Mayotte N, Béliveau F, Lavallée VP, Hébert J, Sauvageau G.   +9 more
europepmc   +1 more source

<i>Ganoderma lucidum</i> alcohol extract targets mutant <i>p53</i> signaling to inhibit proliferation in triple-negative breast brain metastasis cancer. [PDF]

J Cancer
Chien YC, Wu GW, Lin YH, Wu JY, Yu YL.
europepmc   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Serositis as possible manifestation in MDS/AML patients with complex karyotype and TP53 mutation: case series. [PDF]

Ann Hematol
Gugole E, Tamellini E, Jance S, Serafin N, Antonini P, Colato C, Krampera M, Ferrarini I, Tanasi I.   +8 more
europepmc   +1 more source

Hypermucinous Dysplasia in Inflammatory Bowel Disease (IBD): Morphology, Molecular Features, and Its Place in the IBD‐Associated Neoplastic Spectrum

Journal of Digestive Diseases, EarlyView.
This review provides the first comprehensive synthesis focused exclusively on hypermucinous dysplasia, summarizing its histopathologic definition, precursor lesions, clinicopathological associations, molecular features, and diagnostic reproducibility.
Ádám Ferenczi, Tamás Lantos, Anita Sejben   +2 more
wiley   +1 more source

TP53 codon 47 and 72 polymorphisms show no association with HPV in Zimbabwean women living with HIV and histologically confirmed cervical and vulvar disease. [PDF]

Front Reprod Health
Kuguyo O, Pascoe M, Lohmann E, Magwaku T, Mukuku DLT, Mandiriri A, Soko N, Dandara C, Mutasa RM, Fitzpatrick M, Palefsky J, Rounge T, Chirenje ZM, Dube Mandishora RS.   +13 more
europepmc   +1 more source

Management of Advanced Prostate Cancer in the Asia‐Pacific Region: Summary of the Asia‐Pacific Advanced Prostate Cancer Symposium 2025

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Summary of the Asia Pacific Advanced Prostate Cancer Symposium 2025, showing disciplines and diversity of participants, discussion topics (high‐risk localized/locally advanced prostate cancer; PSA persistence and recurrence; radioligand therapy; genetics and genomics; bone protection and other aspects of supportive care), key themes, and high‐level ...
Edmund Chiong, Renu Eapen, Nicholas Buchan, Kenneth Chen, Lukman Hakim, Agus Rizal Hamid, Jae‐Young Joung, Ravindran Kanesvaran, Makarand Khochikar, Jason Letran, Bannakij Lojanapiwat, Indranil Mallick, Chi Fai Ng, Pei Ing Ngam, Teng Aik Ong, Jacob Pang, Darren M. C. Poon, Natasha Roberts, Marniza Saad, Shinichi Sakamoto, Jeremy Tey, Sue Ping Thang, Poh Choo Toh, Levent Türkeri, Nguyễn Tuấn Vinh, Alvin Wong, Yao Zhu, ANZUP Cancer Trials Group, Ian D. Davis   +28 more
wiley   +1 more source

Exploring the prognostic impact and biological functions of mutant-like TP53-related genes in acute myeloid leukemia. [PDF]

Hematol Transfus Cell Ther
Bertoline LMF, Coelho-Silva JL, Lima K, Rego EM, Machado-Neto JA.   +4 more
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source