Results 241 to 250 of about 92,920 (301)

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Endothelial tPA-dependent recruitment of microglia to vessels protects the blood-brain barrier after stroke. [PDF]

Fluids Barriers CNS
Etuzé T, Fosset L, Vivien D, Roussel BD, Lemarchand E.   +4 more
europepmc   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Molecularly sculpted NIR-II nano-igniter converts local photothermal heat into systemic antitumor vaccination. [PDF]

J Nanobiotechnology
Ding Q, Liu T, Xiang C, Wang Q, Li M, Sun Y, Zhang R.   +6 more
europepmc   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Systematic anatomical validation of the endoscopic mononostril transethmoid-paraseptal approach to the central skull base. [PDF]

Brain Spine
Eördögh M, Weidemeier M, Baksa G, Patonay L, Simmen D, Schroeder HWS, El Refaee E, Hosemann W, Reisch R, Briner HR.   +9 more
europepmc   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source

Suicidal Ideation and Attempts in Older Adults: Findings From Five Canadian Emergency Departments

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The main objective of this study was to describe the characteristics of older Emergency Department (ED) patients consulting for suicidal ideation/suicide attempts. The secondary objective was to explore material and social deprivation status in those patients.
Valérie Boucher, Ann‐Pier Gagnon, Pier‐Alexandre Tardif, Matthew Menear, Wendy Thompson, Steven R. McFaull, Audrey‐Anne Dumais‐Michaud, Marcel Émond, Eric Mercier   +8 more
wiley   +1 more source

Hybrid sorghum breeding in China: A historical review and perspectives

Journal of Integrative Plant Biology, EarlyView.
To commemorate the 60th anniversary of the promotion and application of three‐line hybrid sorghum in China, this review highlights pivotal scientific breakthroughs, systematically summarizes the progress in hybrid sorghum breeding and dwarf sorghum breeding in the country, and presents an outlook on the future of sorghum breeding.
Xiangxiang Meng, Lu Li, Qian Qian, Liang Jiang, Zhaosheng Kong   +4 more
wiley   +1 more source

Dopaminergic Identity of SH-SY5Y Cells Across Differentiation Protocols in Parkinson's Disease Research: A Systematic Review. [PDF]

Int J Mol Sci
Artimagnella O, Floramo A, Cipriano GL, Argento V, Lui M.   +4 more
europepmc   +1 more source