Results 271 to 280 of about 270,020 (316)

Multiphoton Absorption Spectra of Channelrhodopsin-2 via Multiscale Simulation Methods. [PDF]

J Chem Theory Comput
Carrasco-Busturia D, Linares M, Norman P, Haugaard Olsen JM.   +3 more
europepmc   +1 more source

Stroke burden and functional impacts in adults with sickle cell disease

British Journal of Haematology, EarlyView.
Stroke was identified in 4.6% of 454 adults with sickle cell disease. Stroke occurred not only across HbSS/Sβ0 phenotypes but also HbSC/Sβ+ as well, challenging traditional assumptions. Stroke was associated with long‐term functional impairment, including cognitive deficits and higher disability scores.
Jonathan St‐Onge, Tzvetena Hristova, Chrystelle Charles, Olena Bereznyakova, Gregory Jacquin, Olivier Pouliot, Janick Caron‐Lecuyer, Mia Stevanovik, Sara‐Maude Desforges, Costa M. Kazadi, Julian Alejandro Rivillas, Christian Stapf, Stéphanie Forté   +12 more
wiley   +1 more source

Electrocoagulation therapy for a patient with an acute thalamoperforating artery pseudoaneurysm: a case report. [PDF]

BMC Cardiovasc Disord
Zhou X, Liu J, Huang G, Zou M, Hu K, Ye X, Zhang Z, Jiang Q.   +7 more
europepmc   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann, Mariana O. Popa, Karen T. Elvers, Misa Oyama, Daniel Ulrich, Marcus Hanley, Gui Jie Feng, Thomas Hathaway, William T. Ralvenius, Thomas Grampp, Dietmar Benke, John R. Atack, Hanns Ulrich Zeilhofer   +12 more
wiley   +1 more source

Agreement and Clinical Utility of the Easytone Transpalpebral Tonometer Compared with Goldmann Applanation, Tono-Pen, and Icare in Healthy Eyes. [PDF]

Diagnostics (Basel)
Kizilay O, Karaca S, Celik G, Yilmaz OF.
europepmc   +1 more source

Neoadjuvant Therapy‐Induced Remodeling in Pancreatic Ductal Adenocarcinoma: Multimodal Spatial Analysis and Prognosis

Cancer Science, EarlyView.
Using integrated spatial pathomics and transcriptomics, we show that neoadjuvant therapy (NAT) in pancreatic ductal adenocarcinoma (PDAC) induces substantial tumor microenvironment remodeling that is not captured by tumor regression grading (TRG) alone.
Xiaofei Zhang, Ruoxin Lan, Danting Li, Yongjun Liu, Sonu Kalyan, Momin Iqbal, Nancy Liu, Jerry Zhang, Iman Hanna, Mala Gupta, Chaohui L. Zhao, Weiguo Liu, Jonathan Melamed, Michael Shusterman, Jessica Widmer, John Allendorf, Yao‐Zhong Liu   +16 more
wiley   +1 more source

Sagittal Alignment Reciprocal Changes After Thoracolumbar/Lumbar Anterior Vertebral Body Tethering. [PDF]

J Clin Med
Yağcı TF, Bayram S, Korkmaz M, Karalar Ş, Bayraktar A, Bayrak G, Akgül T.   +6 more
europepmc   +1 more source

Quantum chemical investigation and molecular design of coumarin-based heavy-metal-free photosensitizers for one- and two-photon excited fluorescence imaging and photodynamic therapy. [PDF]

RSC Adv
Pham TC, Tran DN, Nguyen VT, Pham VT, Tran DL, Lee S.   +5 more
europepmc   +1 more source

On-demand mild photothermal cascade platform reprogramming mitochondrial immunity for tendon rejuvenation. [PDF]

Bioact Mater
Zheng Z, Hu Y, Zhu Y, Zhang H, Yang M, Ding G, Wu Y, Yang F, Lu B, Zhou Z, Liu X, Zhang G, Zhang X, Zhang D, Wang J, Huang H.   +15 more
europepmc   +1 more source