Results 141 to 150 of about 16,561,111 (163)
European Journal of Pharmaceutical Sciences, 2002 The present study was conducted to investigate and compare the effect of pH and drug concentration on nicotine permeability across the TR146 cell culture model and porcine buccal mucosa in vitro. As a further characterization of the TR146 cell culture model, it was explored whether the results were comparable for bi-directional and uni-directional ...
Hanne Mørck Nielsen
exaly +5 more sources
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International Journal of Biological Macromolecules, 2019
Two novel core-shell fibers which could self-assemble liposome were fabricated based on bioadhesive polymer carboxymethyl chitosan (CMCS) and Sodium carboxymethyl cellulose (CMC-Na), separately. The shell layers were CMCS/PVA and CMC-Na/PVA, respectively,
Jian-Ting Chen +4 more
semanticscholar +3 more sources
Two novel core-shell fibers which could self-assemble liposome were fabricated based on bioadhesive polymer carboxymethyl chitosan (CMCS) and Sodium carboxymethyl cellulose (CMC-Na), separately. The shell layers were CMCS/PVA and CMC-Na/PVA, respectively,
Jian-Ting Chen +4 more
semanticscholar +3 more sources
International journal of pharmaceutics, 2000 The objective of the present study was to evaluate the TR146 cell culture model as an in vitro model of human buccal epithelium. For this purpose, the permeability of water, mannitol and testosterone across the TR146 cell culture model was compared to ...
Hanne Mørck Nielsen, M. Rassing
semanticscholar +3 more sources
International Journal of Pharmaceutics, 2015
A salbutamol sulfate (SS)-Poloxamer bioadhesive hydrogel specially developed for buccal administration was investigated by studying interactions with TR146 human buccal epithelium cells (i.e. cellular toxicity (i) and trans-epithelial SS diffusion (ii)).
Ni Zeng +8 more
semanticscholar +3 more sources
A salbutamol sulfate (SS)-Poloxamer bioadhesive hydrogel specially developed for buccal administration was investigated by studying interactions with TR146 human buccal epithelium cells (i.e. cellular toxicity (i) and trans-epithelial SS diffusion (ii)).
Ni Zeng +8 more
semanticscholar +3 more sources
International Journal of Pharmaceutics, 2013
The oral cavity is considered an attractive site of drug administration. Metformin is currently, used in oral diabetes treatment. The aim of the current study was to study the feasibility of metformin, to permeate the buccal epithelium applying a bioadhesive and permeation enhancing drug delivery system.
Jette Bredahl Jacobsen +1 more
exaly +4 more sources
The oral cavity is considered an attractive site of drug administration. Metformin is currently, used in oral diabetes treatment. The aim of the current study was to study the feasibility of metformin, to permeate the buccal epithelium applying a bioadhesive and permeation enhancing drug delivery system.
Jette Bredahl Jacobsen +1 more
exaly +4 more sources
Effect of Laser Therapy on Defensins’ Gene Expression in TR146 Epithelial Cell Line
Protein & Peptide Letters, 2018Introduction: Laser Therapy (LT) has been employed for the treatment of Oral Mucositis (OM) due to its anti-inflammatory, analgesic and bio-stimulatory effects. </P><P> Objective: This pilot study investigated the effect of LT on the expression of DEFB1, DEFB4, DEFB103 genes encoding for the human ...
Zupin, Luisa +6 more
openaire +3 more sources
International Journal of Pharmaceutics, 2000
The objective of the present study was to evaluate the TR146 cell culture model as an in vitro model of human buccal epithelium. For this purpose, the permeability of water, mannitol and testosterone across the TR146 cell culture model was compared to the permeability across human, monkey and porcine buccal mucosa.
Hanne Mørck Nielsen
exaly +3 more sources
The objective of the present study was to evaluate the TR146 cell culture model as an in vitro model of human buccal epithelium. For this purpose, the permeability of water, mannitol and testosterone across the TR146 cell culture model was compared to the permeability across human, monkey and porcine buccal mucosa.
Hanne Mørck Nielsen
exaly +3 more sources
Interaction of differently coated silver nanoparticles with skin and oral mucosal cells.
Journal of Pharmacy and Science, 2021Silver nanoparticles (AgNP) can be found in different consumer products and various medical devices due to their excellent biocidal properties. Despite extensive scientific literature reporting biological effects of AgNP, there is still a lack of ...
K. Ilić +8 more
semanticscholar +1 more source
Drug and Chemical Toxicology, 2011
To find potential enhancers for facilitating the buccal delivery of insulin, a TR146 cell-culture model of buccal epithelium, cultured on commercially available insert plates, was used to evaluate the permeability-enhancing effects of several traditional and new types of chemical enhancers, including N-acetyl-L-cysteine (NAC), sodium deoxycholate (SDC),
Xiao-yan, Xue +8 more
openaire +2 more sources
To find potential enhancers for facilitating the buccal delivery of insulin, a TR146 cell-culture model of buccal epithelium, cultured on commercially available insert plates, was used to evaluate the permeability-enhancing effects of several traditional and new types of chemical enhancers, including N-acetyl-L-cysteine (NAC), sodium deoxycholate (SDC),
Xiao-yan, Xue +8 more
openaire +2 more sources
Forensic Toxicology, 2019
The aim of the present study was to evaluate the cytotoxicity of five synthetic cannabinoids in two cell lines, for which both reference standards and herbal blends were available. An in-house smoking device was developed to produce smoke condensates.
Wolfgang Weinmann +2 more
exaly +2 more sources
The aim of the present study was to evaluate the cytotoxicity of five synthetic cannabinoids in two cell lines, for which both reference standards and herbal blends were available. An in-house smoking device was developed to produce smoke condensates.
Wolfgang Weinmann +2 more
exaly +2 more sources