Results 81 to 90 of about 78,864 (334)

Biomechanical Rigidity and Quantitative Proteomics Analysis of Segmental Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures

open access: yesInvestigative Ophthalmology and Visual Science, 2018
Purpose The extracellular matrix (ECM) of the trabecular meshwork (TM) modulates resistance to aqueous humor outflow, thereby regulating IOP. Glaucoma, a leading cause of irreversible blindness worldwide, is associated with changes in the ECM of the TM ...
Janice A. Vranka   +7 more
semanticscholar   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Corneal alterations associated with pseudoexfoliation syndrome and glaucoma: A literature review [PDF]

open access: yes, 2017
A systematic literature review was performed evaluating articles examining the effects of pseudoexfoliation syndrome (PEX) and glaucoma (PEXG) on the cornea with a focus on the corneal endothelium.
Palko, Joel R   +2 more
core   +7 more sources

The relationship between outflow resistance and trabecular meshwork stiffness in mice

open access: yesScientific Reports, 2018
It has been suggested that common mechanisms may underlie the pathogenesis of primary open-angle glaucoma (POAG) and steroid-induced glaucoma (SIG).
Ke Wang   +7 more
semanticscholar   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim   +5 more
wiley   +1 more source

Glaucoma and cigarette smoking: a review of narrative reviews [PDF]

open access: yes, 2016
Background: Glaucoma is an optic neuropathy associated with visual field changes for which high intra-ocular pressure is a major risk factor. Emerging research indicates that modifiable factors, among which the cigarette smoke, besides IOP may be ...
DI MURRO, FRANCESCA   +3 more
core   +2 more sources

AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer   +3 more
wiley   +1 more source

Isolated anterior-chamber fungal flocculosus in a healthy child with seeding through the trabecular meshwork

open access: yesTNOA Journal of Ophthalmic Science and Research, 2019
We report a case of isolated anterior-chamber (AC) fungal hyphae in a healthy child following injury with a broomstick with no evidence of obvious intraocular penetration, a rare presentation of isolated traumatic AC mycoses.
Manjula Jayakumar, Akshaya Parthasarathy
doaj   +1 more source

Intraocular pressure changes: an important determinant of the biocompatibility of intravitreous implants. [PDF]

open access: yesPLoS ONE, 2011
In recent years, research efforts exploring the possibility of using biomaterial nanoparticles for intravitreous drug delivery has increased significantly. However, little is known about the effect of material properties on intravitreous tissue responses.
Ling Zou   +5 more
doaj   +1 more source

Where does selective laser trabeculoplasty stand now? A review [PDF]

open access: yes, 2016
Background: Chronic treatment of glaucoma can present a challenge in patients who lack the means and/or the discipline to use daily glaucoma medication. We wondered if selective laser trabeculoplasty (SLT) could be a useful alternative.
De Belder, Maya   +3 more
core   +2 more sources

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