Results 31 to 40 of about 4,900,225 (242)

Current Trends of Essential Trace Elements in Patients with Chronic Liver Diseases

Nutrients, 2020
Essential trace elements play crucial roles in the maintenance of health, since they are involved in many metabolic pathways. A deficiency or an excess of some trace elements, including zinc, selenium, iron, and copper, frequently causes these metabolic ...
T. Himoto, T. Masaki
semanticscholar   +1 more source

CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences

Cells, 2019
Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger.
Ekaterina Y. Ilyechova, Elisa Bonaldi, Iurii A. Orlov, Ekaterina A. Skomorokhova, Ludmila V. Puchkova, Massimo Broggini   +5 more
doaj   +1 more source

An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder

International Journal of Bipolar Disorders, 2020
Background Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. Methods We conducted an integrative analysis of genome-wide association study (GWAS) and regulatory SNP (rSNP) annotation datasets ...
Xin Qi, Yan Wen, Ping Li, Chujun Liang, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, Li Liu, Om Prakash Kafle, Feng Zhang   +10 more
doaj   +1 more source

Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China

Arthritis Research & Therapy, 2022
Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning, Minhan Hu, Yi Gong, Ruitian Huang, Ke Xu, Sijie Chen, Feiyu Zhang, Yanli Liu, Feihong Chen, Yanhai Chang, Guanghui Zhao, Cheng Li, Rong Zhou, Mikko J. Lammi, Xiong Guo, Xi Wang   +15 more
doaj   +1 more source

Longitudinal relationship between body fat percentage and risk of type 2 diabetes in Chinese adults: Evidence from the China Health and Nutrition Survey

Frontiers in Public Health, 2022
ObjectiveBody fat percentage (BF%) might be an alternative index of obesity which is the major risk factor for developing type 2 diabetes (T2D). We aim to longitudinally evaluated the relationship between BF% and risk of T2D.MethodsA sample of 5,595 ...
Siting Zhang, Hongru Jiang, Hongru Jiang, Liusen Wang, Liusen Wang, Xiaofang Jia, Xiaofang Jia, Jiguo Zhang, Jiguo Zhang, Huijun Wang, Huijun Wang, Bing Zhang, Bing Zhang, Zhihong Wang, Zhihong Wang, Gangqiang Ding, Gangqiang Ding   +16 more
doaj   +1 more source

Evaluating the effect of birth weight on brain volumes and depression: An observational and genetic study using UK Biobank cohort

European Psychiatry, 2020
Background.Birth weight influences not only brain development, but also mental health outcomes, including depression, but the underlying mechanism is unclear.Methods.The phenotypic data of 12,872–91,009 participants (59.18–63.38% women) from UK Biobank ...
Jing Ye, Cuiyan Wu, Xiaomeng Chu, Yan Wen, Ping Li, Bolun Cheng, Shiqiang Cheng, Li Liu, Lu Zhang, Mei Ma, Xin Qi, Chujun Liang, Om Prakash Kafle, Yumeng Jia, Sen Wang, Xi Wang, Yujie Ning, Feng Zhang   +17 more
doaj   +1 more source

A black shale protolith for gold-tellurium mineralisation in the Dalradian Supergroup (Neoproterozoic) of Britain and Ireland [PDF]

, 2017
The Dalradian Supergroup of Britain and Ireland is mineralised by gold-tellurium vein deposits. The host succession includes carbonaceous, pyritic shales (pelites) which were a source of trace elements, including gold and tellurium.
Armstrong, J., Boyce, A.J., Bullock, L., Feldmann, J., Parnell, J., Perez, M.   +5 more
core   +1 more source

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis

Arthritis Research & Therapy, 2021
Objective To identify rheumatoid arthritis (RA)-associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. Methods A transcriptome-wide association study (TWAS) was conducted by
Cuiyan Wu, Sijian Tan, Li Liu, Shiqiang Cheng, Peilin Li, Wenyu Li, Huan Liu, Feng’e Zhang, Sen Wang, Yujie Ning, Yan Wen, Feng Zhang   +11 more
doaj   +1 more source

Water quality of Texas bays (nutrients, trace elements and toxic compounds) [PDF]

, 1974
This manuscript is designed to compare the nutrient balances and trace element significance in Texas Bays and Estuaries. The task of assigning water quality criteria in all estuarine waters rests with the federal Environmental Protection Agency. However,
Brogden, William B., Isensee, Thomas, Oppenheimer, Carl H.   +2 more
core   +1 more source

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis

Scientific Reports, 2017
Kashin-Beck disease (KBD) is a chronic osteochondropathy with unclear pathogeny. In this study, we compared the microRNA expression profiles of 16 KBD patients, 16 osteoarthritis (OA) patients and 16 rheumatoid arthritis (RA) patients and 16 healthy ...
Wenhong Wu, Awen He, Yan Wen, Xiao Xiao, Jingcan Hao, Feng Zhang, Xiong Guo   +6 more
doaj   +1 more source