Results 91 to 100 of about 166,926 (278)

A Systematic Review of Tracing Solutions in Software Product Lines [PDF]

, 2018
Software Product Lines are large-scale, multi-unit systems that enable massive, customized production. They consist of a base of reusable artifacts and points of variation that provide the system with flexibility, allowing generating customized products.
Asri, Bouchra El, Kriouile, Abdelaziz, Mcharfi, Zineb   +2 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Simultaneous determination of 11 haloacetic acids and oxyhalides by UPLC-HRMS in Human Serum, Breast Milk, and Urine

Talanta Open
Disinfection byproducts (DBPs), particularly haloacetic acids (HAAs) and oxyhalides, are of global concern due to their carcinogenicity and occurrence beyond drinking water.
Zelin Wang, Xiaoyu Hu, Qiaozhen Guo, Mengdie Fan, Yang Xing, Sai Fan, Yunjia Yang, Jing Zhang, Bing Shao   +8 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Traceability as Part of Competitive Strategy in the Fruit Supply Chain [PDF]

This paper discusses traceability as part of information management in fruit supply chains of Emilia-Romagna, Italy. A review of the rules in use for traceability distinguishes between a proper traceability and a traceability plus (T+), embedded of many ...
Canavari, Maurizio, Centonze, Roberta, Spadoni, Roberta   +2 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Safety Risk Assessment and Classification of Cadmium in Grain Processing Products

Foods
As a staple food for people worldwide, processed grain products, including rice, wheat flour, etc., have been the major source of the toxic element cadmium for human exposure.
Qingchuan Zhang, Wenjie Dou, Zheng Wang, Xuemei Xu, Tongqiang Jiang   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Rapid Screening for Hazardous Substances with Regulatory Differences in Milk Between Countries Using Ultra-High Performance Liquid Chromatography Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry

Foods
Regulatory heterogeneity on the maximum residue levels (MRLs) of hazardous substances for food is identified as a challenge of trade between countries. To balance the import and export trade of milk, a high-throughput determination method was established
Qiaozhen Guo, Jing Zhang, Bing Shao, Jie Yin, Yunjia Yang, Yi Yang   +5 more
doaj   +1 more source