Results 31 to 40 of about 38,375 (219)

Modeling Graph Neural Networks and Dynamic Role Sorting for Argument Extraction in Documents

open access: yesApplied Sciences, 2023
The existing methods for document-level event extraction mainly face two challenges. The first challenge is effectively capturing event information that spans across sentences.
Qingchuan Zhang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

An Effective Pyramid Neural Network Based on Graph-Related Attentions Structure for Fine-Grained Disease and Pest Identification in Intelligent Agriculture

open access: yesAgriculture, 2023
In modern agriculture and environmental protection, effective identification of crop diseases and pests is very important for intelligent management systems and mobile computing application.
Sen Lin   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Named entity recognition and coreference resolution using prompt-based generative multimodal

open access: yesComplex & Intelligent Systems
Named Entity Recognition (NER) and Coreference Resolution (CR) are both of pivotal significance in the domain of natural language processing. The accurate detection of pronouns and noun phrases has been shown to have a direct impact on cross-sentence and
Qingchuan Zhang   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Cadmium exposure assessment based on food survey data in an urban area of Beijing and Chongli area of Zhangjiakou

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveTo provide a reference for food safety risk assessment and safety assurance for the Winter Olympics and Beijing residents, the exposure level and possible health risks of cadmium (Cd) in main foods in the surrounding areas of the 2022 Beijing ...
HAN Gaochao   +18 more
doaj   +1 more source

Home - About - Disclaimer - Privacy