Results 51 to 60 of about 147,122 (268)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Jurnal Analisis Bisnis Ekonomi, 2018 Penelitian ini bertujuan untuk mengidentifikasi profil pekerjaan lulusan yang meliputi kesesuaian pekerjan dengan bidang studi, masa tunggu lulusan, motivasi bekerja, gaji yang diterima dan lama masa studi mahasiswa.
Anissa Hakim Purwantini +2 more
doaj +1 more source
13N as a tracer for studying glutamate metabolism [PDF]
Neurochemistry International, 2011 This mini-review summarizes studies my associates and I carried out that are relevant to the topic of the present volume [i.e. glutamate dehydrogenase (GDH)] using radioactive (13)N (t(1/2) 9.96 min) as a biological tracer. These studies revealed the previously unrecognized rapidity with which nitrogen is exchanged among certain metabolites in vivo ...
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Faces, Changes, ad Places: Tracing the Journey of Master Language Educators
Diversitas Journal, 2023 Professional development like finishing graduate or post-graduate degrees is one of the key indicators of advancement in the practice of one’s profession.
Mildred M. Crisostomo
doaj
The Journal of Indian Prosthodontic Society, 2005 PURPOSE: Centric and eccentric relations of mandible can be recorded through check bites, graphic recordings, functional recordings and cephalometrics. These records are then transferred to a semi-adjustable articulator so that it can be set to simulate the human system.
VV Nandini +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
PENELUSURAN PROFIL LULUSAN TAHUN 2015-2017 JURUSAN KIMIA FMIPA UNNES
Jurnal Inovasi Pendidikan Kimia, 2018 Dua Program Studi di Jurusan Kimia FMIPA UNNES memperoleh status akreditasi A pada tahun 2016. Dalam rangka mempertahankan status akreditasi unggul tersebut, maka Jurusan Kimia memandang perlu melakukan upaya berkelanjutan untuk mengumpulkan informasi ...
Jumaeri Jumaeri +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source