Results 71 to 80 of about 178,356 (314)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
PURPOSE: Centric and eccentric relations of mandible can be recorded through check bites, graphic recordings, functional recordings and cephalometrics. These records are then transferred to a semi-adjustable articulator so that it can be set to simulate the human system.
VV Nandini +3 more
openaire +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
One of the indicators of a developed faculty is the numbers of department organized by the faculty. In order to develop the faculty, the Faculty of Social and Political Sciences, the State Islamic University Walisongo had planned to prepare a new ...
Muhyar Fanani +3 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Application of planar laser-induced fluorescence measurement techniques to study the heat transfer characteristics of parallel-plate heat exchangers in thermoacoustic devices [PDF]
This paper describes the development of an experimental arrangement and the application of acetone-based planar laser-induced fluorescence (PLIF) measurement techniques to study the unsteady characteristics of heat transfer processes in the parallel ...
Artur J Jaworski +8 more
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The overall performance of a wastewater treatment plant is in addition to the effectiveness of the biokinetic processes controlled by the flow dynamics. A wide used technique to characterize the water flow dynamics is the use of tracers.
Andrés Alvarado +3 more
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Education, Employment and Earnings of Secondary School-Leavers in Tanzania: Evidence from a Tracer Study [PDF]
The extent of information on labour market outcomes and the earnings of educated groups in Tanzania, and Sub-Saharan Africa more generally, are limited.
Samer Al-Samarrai, Barry Reilly
core

